Study subjects will use betadine saline sinus rinse for period of 6 weeks.

Chronic Rhinosinusitis (Diagnosis)

Povidone Iodine solution 5% (0.5% available iodine) by 3MTM has been specially formulated as a nasal antiseptic. They have shown topical application to be clinically safe, tolerable and to be rapidly bacteriocidal against aerobic gram positive and gram- negative bacteria including methicillin resistant Staphylococcus aureus, methicillin resistant Staphylococcus epidermidis, vancomycin resistant Enterococcus faecium and Enterococcus faecalis (VRE) and yeast (3M study 05-011100,05-011017, 05-011322).

Povidone-Iodine

Budesonide is is provided in nebules (1mg/2cc). Patients will place two nebules of budesonide into the 250mls of saline.

Budesonide

St. Paul's Hospital

Betadine Rinses for Chronic Rhinosinusitis Prospective Cohort Study

The Efficacy of Topical Povidone - Iodine Rinses in the Management of Biofilm-associated Chronic Rhinosinusitis

differences in Modified Lund-Kennedy (MLK) endoscopic score after 6 weeks of using Povidone-iodine (PVP-I) sinus rinses.

disease specific quality of life questionnaire score (SNOT-22) in recalcitrant/recurrent CRS patients

We will publish final outcomes as scientific paper.

Amin Javer

Clinical Professor

St. Paul's Hospital, Canada

In this arm, the children received, orally, the combination of midazolam and ketamine. Midazolam, at a dose of 0.5 mg/kg (maximum dose 20 mg) and ketamine, at a dose of 3 mg/kg (maximum dose 50 mg). This combination of drugs were administered fifteen minutes before the start of treatment sessions.

In this arm, the children received, orally, the combination of midazolam and ketamine. Midazolam, at a dose of 0.5 mg/kg (maximum dose 20 mg) and ketamine, at a dose of 3 mg/kg (maximum dose 50 mg). After fifteen minutes of this drug administration, the investigators start to provide sevoflurane, through a nasal hood, in an initial concentration of 0.1%, with 0.1% increment every 30 seconds, until a final expired concentration between 0.3 and 0.4%.

Dental Anxiety

The combination of these three drugs were administered for the children of the intervention group in a attempt to improve the behavioral control. Midazolam and ketamine orally, sevoflurane inhaled.

Midazolam, Ketamine and Sevoflurane

The combination of these two drugs were administered orally for the children of the control group.

Midazolam and Ketamine

A large epidemiological survey on the oral status of the Brazilian population. Developed by the Department of Primary Health Care of the Ministry of Health in 2010.

Faculty of Dentistry

Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation

Use of Sevoflurane, Midazolam and Ketamine in Children for Dental Sedation Treatment: Occurrence of Adverse Events

Evaluate the occurrence of adverse events during restorative dental treatment and in the first 24 hours after sedation with midazolam, ketamine and sevoflurane in children four to six years.

Evaluate the behavioral control of children undergoing sedation with midazolam, ketamine and sevoflurane during dental treatment.

The research data can be shared with other researchers at a reasonable request.

amnesia/karies gigi

Betadine Rinses for Chronic Rhinosinusitis Prospective Cohort Study

Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation

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