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Complementary Intervention for COVID-19
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Since last December 2019, a syndrome of severe pneumonia associated with the coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei Province, China. It is highly contagious and rapidly spread to many other parts of China and almost all countries all over the world, representing one of the most
DISulfiram for COvid-19 (DISCO) Trial
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The identification of a safe, effective treatment for individuals with early mild-to-moderate symptomatic COVID-19 that prevent progression to more severe disease would have immediate public health implications. A hallmark of severe COVID-19 disease is immune system dysregulation called cytokine
COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients
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This is a prospective multicenter interventional observational study will be conducted in 4 major tertiary hospitals (Al-Sabah, Farwaniya , Mubarak Al-Kabeer and Jahra) in Kuwait .
Safety and Efficacy of Maraviroc and/or Favipiravir vs Standard Therapy in Severe COVID-19 Adults
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The COVID-19 pandemic (Coronavirus Disease-19) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has caused more that 10 million infections worldwide, with a general mortality of 6%. Multiple studies have found that the hyperinflammatory immune response induced by SARS-CoV-2 is
A Multi-Center Study Evaluating Clinical Course in Patients With COVID19 and Its Relationship to Cytokine Storm
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Study Rationale
Over 100 patients were hospitalized at Hadassah in the recent 2 months with the diagnosis of COVID19.
We would like to summarize the clinical outcomes and their correlation to a cytokine storm at Hadassah and additional hospitals and additional hospitals in Israel.
COVID-19, the name
Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial
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This is a prospective 1:1 randomized open-label clinical trial to investigate the safety and efficacy of the combination of Colchicine + Rosuvastatin added to standard of care (SOC) compared to SOC alone in hospitalized subjects with moderate COVID-19.
Subjects will be screened during admission to
The Use of Brazilian Green Propolis Extract (EPP-AF) in Patients Affected by COVID-19.
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Combination Therapies to Reduce Carriage of SARS-Cov-2 and Improve Outcome of COVID-19 in Ivory Coast: a Phase Randomized IIb Trial
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The Study of Quadruple Therapy Zinc, Quercetin, Bromelain and Vitamin C on the Clinical Outcomes of Patients Infected With COVID-19
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Efficacy and Safety of Sirolimus in COVID-19 Infection
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In early December 2019, several pneumonia cases of unknown origin were observed in Wuhan (China). A novel enveloped RNA β coronavirus was isolated and named severe acute respiratory syndrome coronavirus 2 (SARSCoV- 2). The new virus rapidly spread across China and worldwide. On March 11th 2020, the
PREPARE-IT. Prevention of COVID19 With EPA in Healthcare Providers at Risk - Intervention Trial
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For the time being, social distancing is probably the only beneficial strategy to reduce infection rates and, consequently, COVID-19-associated morbidity and mortality. To date, there is no available effective treatment to avoid or reduce infection (vaccines or viral inhibitors), to reduce or
Hypertonic Saline for COVID-19 Symptoms
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Since its emergence as severe outbreak in China in December 2019, coronavirus disease 2019 (COVID-19) has spread so rapidly in the world that more than 780,000 cases have so far been reported worldwide and since then the WHO has declared it as a pandemic. The rapid spread of the disease is imposing
Therapeutic Plasma Exchange in Resistant Cytokine Storm of COVID 19
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In early December 2019, several pneumonia cases of unknown origin were observed in Wuhan (China). A novel enveloped RNA β coronavirus was isolated and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The new virus rapidly spread across China and worldwide. On March 11th 2020, the
Rehabilitation Needs and Functional Recovery in Covid-19 Acute and Post-acute Care
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The disease caused by SARS-CoV-2 infection, COronaVIrus Disease-19 (COVID-19), was first reported on December 31, 2019. About 20% patients, mostly elderly people, suffered from a severe form of acute respiratory failure. COVID-19 is a new clinical entity, therefore its understanding is largely
Effect of Hepatitis C Clearance on Insulin Resistance
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the link between hepatitis C infection and insulin resistance has been established. Insuli resistance has been linked to poor response to interferon based therapy. recently, direct acting antiviral drugs are approved for hepatitis C elimination with high potency and safety. The aim of the study is
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