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Chat-based Support for Preveting Smoking Relapse

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Smoking cessation is one of the most cost-effective health interventions, which can add up to 10 years of life expectancy (Jha et al., 2013). However, it is very difficult to quit smoking because of the addictive effect of nicotine presents in tobacco products, and smokers typically make multiple
COVID-19 (Corona Virus Disease 2019) is a virulent infectious disease with an incubation period ranging between 2-14 days. This highly contagious disease is caused by Sars-Cov-2 (Severe Acute Respiratory Syndrome Coronavirus 2). The number of people infected by COVID-19 has increased exponentially

Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients

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Based on the information gained in previous studies the investigators want to examine if; A. anti-inflammatory treatment that target TNF-α or JAK signalling or B. physical training of hands has a positive impact on neuropsychiatric symptoms and morphological changes in the brain caused by RA. To

Effect of Mindfulness on Opioid Use and Anxiety During Primary Care Buprenorphine Treatment (R33 Phase)

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The investigators will conduct a multi-site randomized comparative effectiveness trial comparing Mindful Recovery Opioid Care Continuum (M-ROCC), a 24-week motivationally-responsive, trauma-sensitive, Group-Based Opioid Treatment (GBOT) program to standard GBOT, on number of biochemically confirmed

The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults

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Scientific background Tobacco smoking is a major health problem, leading to considerable morbidity and mortality due to cancer, pulmonary illnesses, and cardiovascular diseases (Taghizadeh, Vonk & Boezen, 2016). The main psychoactive and addictive substance in tobacco is nicotine (Zaparoli &
C.2 Subject Inclusion and Assessments Overall study design: Non-EC-naïve smokers or e-cigarette users (n=20) will abstain from tobacco smoking/nicotine products for 5 days prior to each PET scan. In a randomized order (counterbalanced), after baseline quantification of receptor availability,

Integrating Motivational Interviewing With Cognitive-behavioral Therapy

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The Effectiveness of Nintendo Wii Fit and Inspiratory Muscle Training in Older Patients With Heart Failure

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NAME OF THE RESEARCH: The Effectiveness of Inspiratory Muscle Training and Nintendo Wii Fit Applications in Elderly Patients with Heart Failure JUSTIFICATION AND BASIS OF THE RESEARCH: Heart failure is a multisystem syndrome characterized by the body's inability to pump or increase the filling

8-week of PS128 RCT in Patients With Major Depressive Disorder

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The eligible patients will be randomly assigned to either active (PS128) or identical-appearing placebo capsule in an 1 : 1 ratio. A research assistant who is blind to the status of participants will conduct the randomization allocation. Recruited patients will be randomized in 1:1 ratio, by a

TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol

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Hypothesis: A "high-intensity" smoking cessation intervention is superior in leading to permanent (>12 months) smoking cessation in active smokers with COPD than does a standard, guideline-based municipal smoking cessation intervention. Secondary hypothesis: The progression of COPD will be reduced

Perioperative Analgesic Efficiency of Quadratus Lumborum Block vs Epidural in Radical Cystectomy

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1. Background and rationale: Bladder cancer is the ninth most common cancer in the world while being considerably common in both developed and developing countries. Bladder cancer is the most common malignancy among Egyptian males and it had been previously attributed to Schistosoma infection, a

The Approach and Avoidance Task (AAT) in Smoking Cessation

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The approach and avoidance task (AAT) has turned out as both a promising diagnostic tool as well as treatment add-on in psychological science. The AAT constitutes one form of cognitive bias modification (CBM), which has been shown to be particularly effective in the field of behavioural addictions

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study

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Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression. Despite this, nearly 50% of COPD patients continue to smoke following diagnosis. Smokers with COPD report high rates of co-occurring

Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery

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BACKGROUND AND AIMS: Open spina bifida or myelomeningocele (MMC) is a devastating congenital defect of the central nervous system for which there is no cure. The etiology of MMC remains poorly understood. Primary failure of neural tube closure at the caudal neuropore in the embryonic period results

Student Wellness Workshop Study

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The transition from adolescence to adulthood, particularly for college students, is accompanied by several major life changes and challenges. For many individuals, this is a period when one moves away from home, begins interacting with different peer groups, and has greater financial and academic
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