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Anti-depressant activities of Areca catechu fruit extract.
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The hexane and aqueous fractions of Areca catechu (A. catechu) have demonstrated anti-depressant properties in screens used to detect such activity. Similar properties had previously been detected in the plant's aqueous ethanolic extract. The aqueous ethanolic extract (F(1)), and the hexane (F(2))
Potential antidepressant activity of Areca catechu nut via elevation of serotonin and noradrenaline in the hippocampus of rats.
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The current study was aimed at investigating the potential antidepressant activity of Areca catechu nut ethanol extract and its various fractions using behavioral (acute and sub-chronic forced swim tests) and biochemical (monoamines and their metabolite levels using high performance liquid
The Aqueous Fraction of Areca catechu Nut Ameliorates Demyelination in Prefrontal Cortex-Induced Depressive Symptoms and Cognitive Decline through Brain-Derived Neurotrophic Factor-Cyclic Adenosine Monophosphate Response Element-Binding Activation.
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OBJECTIVE
To investigate if Areca catechu L. treatment could ameliorate depressive symptoms and cognitive decline by facilitating myelination processes in prefrontal cortex.
METHODS
A mouse model of cuprizoneinduced demyelination was used to mimic demyelinating disease. Two concentrations of A.
Behavioral and biochemical studies of dichloromethane fraction from the Areca catechu nut.
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The dichloromethane fraction from Areca catechu was found to inhibit monoamine oxidase type A isolated from the rat brain with an IC50 of 665 +/- 65.1 microg/ml. Studies with pharmacological models of depression, i.e., forced swim and tail-suspension tests, indicated that it caused significant
Herb-drug interactions.
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Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin
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