attention deficit hyperactivity disorder/demam

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Fever and infections in pregnancy and risk of attention deficit/hyperactivity disorder in the offspring.

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BACKGROUND Fever and infections are common events during pregnancy, and have been shown to be associated with neurodevelopmental impairment in the offspring. The evidence in relation to attention deficit/hyperactivity disorder (ADHD) is, however, nonexistent for fever and limited for infections. The

Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.

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The tetrahydroisoquinoline trabectedin is a marine compound with approved activity against human soft-tissue sarcoma. It exerts antiproliferative activity mainly by specific binding to the DNA and inducing DNA double-strand breaks (DSB). As homologous recombination repair (HRR)-deficient tumors are

Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder.

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Maternal fever during pregnancy is associated with several adverse child outcomes. We investigated associations between maternal fever and ADHD among offspring, as well as the sub-dimensions of ADHD - inattention and hyperactivity/impulsivity. Data came from the Norwegian Mother and Child Cohort

Hyperthermia adds to chemotherapy.

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The hallmarks of hyperthermia and its pleotropic effects are in favour of its combined use with chemotherapy. Preclinical research reveals that for heat killing and synergistic effects the thermal dose is most critical. Thermal enhancement of drug cytotoxicity is accompanied by cellular death and

Combined modality therapy with bleomycin, hyperthermia, and radiation.

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In an attempt to develop better combination therapies for use with local radiation, the interaction between bleomycin and hyperthermia +/- radiation was studied in the FSaIIC tumor system. In cells exposed in vitro to bleomycin at 37 degrees C and at pH 7.40, the drug was substantially more toxic

Comparison of Relation between Attention Deficit Hyperactivity Disorder in Children with and without Simple Febrile Seizure Admitted in Arak Central Iran.

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OBJECTIVE Febrile seizure is one of the most prevalent childhood convulsions with the most common age of onset at 14-18 mo old. Fever decreases the brain threshold for seizure. Attention Deficit Hyperactivity Disorder (ADHD) is also a neurologic-behavioral problem defined by attention deficit and

Coagulation abnormalities in dengue and dengue haemorrhagic fever patients.

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The aim of this study was to assess abnormality of coagulation and anticoagulation parameters in dengue fever patients and the impact of these tests on the management of patients.Dengue fever is endemic in Pakistan with seasonal rise in cases. Morbidities

Genital ulcers as an unusual sign of periodic fever, aphthous stomatitis, pharyngotonsillitis, cervical adenopathy syndrome: a novel symptom?

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Periodic fever, aphthous stomatitis, pharyngotonsillitis, cervical adenopathy (PFAPA) syndrome, which is characterized by periodic episodes of high fever, aphthous stomatitis, pharyngitis, and cervical adenitis, is of unknown etiology and manifests usually before 5 years of age. A patient with

Blood cultures for assessment of postoperative fever in arthroplasty patients.

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Postoperative fever in arthroplasty patients is common. The value of diagnostic workup of fever in this instance is of questionable utility. Studies have shown that blood cultures in this scenario add little to clinical management, but sample sizes have been small and the use of blood cultures in

Side-effects of local hyperthermia: results of a prospectively randomized clinical study.

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In 1986, 25 patients with stage II and III carcinoma of the cervix were treated by a combination of radiation and local hyperthermia using an endotract intravaginal applicator. Another 25 patients were treated with radiation alone. Both groups were followed up for a minimum period of 18 months. The

Assessment of palliative response in hyperthermia.

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It is important that clinical studies of hyperthermia will be able to define its contribution to palliative therapy. A variety of validated methods has been developed for assessing palliative therapy but none have been used in clinical studies of hyperthermia. In the present paper some of the

LASSA FEVER IN PREGNANCY WITH A POSITIVE MATERNAL AND FETAL OUTCOME: A CASE REPORT.

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Lassa fever is a rodent-borne zoonosis that clinically manifests as an acute haemorrhagic fever. Surviving Lassa fever during pregnancy is rare. Only few cases have been documented to date. It is treated using ribavirin.We report a case of a 25-year old

Effect of a mu-opioid receptor-selective antagonist on interleukin-6 fever.

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The endogenous opioid system has been found to be involved in fever caused by pyrogens. Recent work in our laboratory has demonstrated that the mu-opioid receptor is involved in interleukin-1beta (IL-1beta)- and in lipopolysaccharide (LPS)-induced fevers. In the present study, we have investigated

Progress in the overall understanding of typhoid fever: implications for vaccine development.

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Introduction: Typhoid fever continues to have a substantial impact on human health, especially in Asia and sub-Saharan Africa. Access to safe water, and adequate sanitation and hygiene remain the cornerstone of prevention, but these are not widely available in many impoverished settings. The

Bickerstaff's brainstem encephalitis associated with typhoid fever.

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A 14 year old boy developed the syndrome of Bickerstaff's brainstem encephalitis during the course of bacteriologically proved typhoid fever. The clinical course and the results of various neurological investigations are detailed. This report adds a further manifestation to the published

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