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Halaman 1 dari 17 hasil
Benzene compounds
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to benzene compounds, and more particularly, to novel benzene compounds having inhibition activity on acetyl CoA carboxylase ("ACC" hereinafter).
2. Discussion of the Background
It has become clear in recent years
2-alkyloxy benzene formyl arylamine compound and pharmaceutical use thereof
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TECHNICAL FIELD
The present invention belongs to the field of medicinal chemistry, which is about the 2-alkoxy benzene formyl arylamine compounds and their pharmaceutical uses, especially the 2-alkoxy benzene formyl arylamine compounds and their uses in preparing sphingomyelin synthase inhibitors,
Lipoprotein lipase-activating compositions comprising benzene derivates
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TECHNICAL FIELD
The present invention relates to compositions for activating lipoprotein lipase (hereinafter referred to as "LPL") and benzene compounds. The invention is further directed to the use of compounds activating LPL for preparing LPL-activating compositions, and a method for activating
Substituted benzene compounds as modulators of the glucocorticoid receptor
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PRIORITY TO RELATED APPLICATION(S)
This application claims the benefit of European Patent Application No. 09156260.3, filed Mar. 26, 2009, which is hereby incorporated by reference in its entirety.
BACKGROUND OF THE INVENTION
Glucocorticoids are responsible for several physiological functions
1,1'-(1,2-ethynediyl)bis-benzene derivatives as PTP 1-B inhibitors
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FIELD OF THE INVENTION
The present invention is related to carboxylic acids of formula (I), in particular for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance,
Fused heterocyclic compounds
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FIELD OF THE INVENTION
The present invention relates to compounds and compositions useful in the treatment of conditions and disorders associated with eating behavior, energy homeostasis and anxiety.
BACKGROUND OF THE INVENTION
G-protein coupled receptors play important roles in diverse signaling
Benzoxathiin derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a U.S. National Phase application under 35 U.S.C. .sctn.371 of PCT Application No. PCT/JP2006/321813, filed Oct. 25, 2006, which claims priority under 35 U.S.C. .sctn.119 from JP Application No. JP2005-312956, filed Oct. 27, 2005.
TECHNICAL
Spiro imidazoline compounds
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FIELD OF THE INVENTION
The present invention relates to new Spiro imidazoline compounds, and to their use as .alpha.2-adrenergic antagonists and monoamine reuptake blockers.
DESCRIPTION OF THE PRIOR ART AND BACKGROUND OF THE INVENTION
The adrenergic nervous system plays an important role at a number
Melanin-concentrating hormone antagonist
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This application is the National Phase filing of International Patent Application No. PCT/JP01/04015, filed 15 May 2001.
TECHNICAL FIELD
The present invention relates to a melanin-concentrating hormone antagonist which is useful as an agent for preventing or treating obesity, etc.
BACKGROUND
Aromatic heterocyclic compound
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TECHNICAL FIELD
The present invention relates to an aromatic heterocyclic compound or a pharmaceutically acceptable salt thereof having an acylcoenzyme A: diacylglycerolacyltransferase (DGAT) 1 inhibitory activity.
BACKGROUND ART
Obesity is a condition wherein fat is excessively accumulated in a
Aromatic heterocyclic compound
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TECHNICAL FIELD
The present invention relates to an aromatic heterocyclic compound or a pharmaceutically acceptable salt thereof having an acylcoenzyme A: diacylglycerolacyltransferase (DGAT) 1 inhibitory activity.
BACKGROUND ART
Obesity is a condition wherein fat is excessively accumulated in a
Azulene derivatives and salts thereof
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Phase Application based on PCT/JP2003/009868, filed on Aug. 4, 2003, the content of which is incorporated herein by reference, and claims the priority of Japanese Patent Application Nos. 2002-226869, filed on Aug. 5, 2002, and
Propanolamine derivative having 1, 4-benzodioxane ring
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This application is a 371 of PCT/JP01/07951 filed Sep. 13, 2001.
TECHNICAL FIELD
This invention relates to novel propanolamine derivatives having a 1,4-benzodioxane ring and medicaments containing them as active ingredients. The derivatives are useful as prophylactic or therapeutic agents for
3-hydroxy-5-arylisoxazole derivative
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TECHNICAL FIELD
The present invention relates to a compound for modulationg the functions of G protein-coupled receptor 40 (GPR40). In particular, the present invention relates to a 3-hydroxy-5-arylisoxazole compound of Formula (I), a salt of the compound, a solvate of the compound or the salt, a
3-hydroxy-5-arylisothiazole derivative
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TECHNICAL FIELD
The present invention relates to a compound for modulating the functions of G protein-coupled receptor 40 (GPR40). In particular, the present invention relates to a compound having a 3-hydroxy-5-arylisothiazole ring of Formula (I), a salt of the compound, a solvate of the compound or
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