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This invention relates to novel heterocyclic compounds possessing 5-lipoxygenase/cyclooxygenase inhibitory and leukotriene antagonist activity, which are useful as anti-inflammatory and antiallergic agents.
It is known that arachidonic acid (AA) is metabolized in mammals by two distinct pathways.
BACKGROUND OF THE INVENTION
1. Field
This invention relates to an external anti-inflammatory and analgesic agent. More particularly, it is concerned with an external anti-inflammatory and analgesic plaster preparation wherein a salt of diclofenac with a cyclic organic base is contained as an active
The present invention relates to a process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use.
EP0621263, in the joint name of Teikoku and the present applicant Altergon, describes a formulation suitable for
Growth factors comprise a family of polypeptides with a manyfold of properties regulating for example cell proliferation and cell metabolism. As being multi-functional molecules, they may stimulate or inhibit cell proliferation as well as affect cell function depending on the type of the target
FIELD OF THE INVENTION
This present invention is related to the use of azolidinone-vinyl fused-benzene derivatives of formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral
FIELD OF THE INVENTION
Embodiments of the present invention relate to methods for the treatment of systemic inflammation. More particularly, embodiments of the present invention relate to a method of intralumenal adsorption of mediators of inflammation comprising administering to a patient a
FIELD OF THE INVENTION
Embodiments of the present invention relate to methods for the treatment of systemic inflammation. More particularly, embodiments of the present invention relate to a method of intralumenal adsorption of mediators of inflammation comprising administering to a patient a
FIELD OF THE INVENTION
The invention relates to substituted benzothiazoles, benzoxazoles--and their counterparts having pyridine and pyrimidine rings replacing the benzene ring--that are useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical
BACKGROUND OF THE INVENTION
1. Field of Invention
The present invention is concerned with the use of certain arylsulfonamides in the treatment of joint disease associated with chronic arthritis methods and pharmaceutical compositions therefore. In particular the invention is concerned with internal
BACKGROUND OF THE INVENTION
The present invention relates to novel benzene butyric acid compounds and their derivatives useful as pharmaceutical agents, to methods for their production, to pharmaceutical compositions which include these compounds and a pharmaceutically acceptable carrier, and to
BACKGROUND OF THE INVENTION
The present invention relates to novel benzene butyric acid compounds and their derivatives useful as pharmaceutical agents, to methods for their production, to pharmaceutical compositions which include these compounds and a pharmaceutically acceptable carrier, and to
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a process for the production of benzene derivatives of chemical formula (I), which are useful as intermediates for agricultural chemicals, fine chemicals or pharmaceuticals such as anti-inflammatory analgesics.
BACKGROUND OF THE INVENTION
Research in the area of allergic reactions of the lung has provided evidence that arachidonic acid derivatives formed by the action of lipoxygenases are related to various disease states. Some of these arachidonic acid metabolites have been classified as members of a
BACKGROUND OF THE INVENTION
Research in the area of allergic reactions of the lung has provided evidence that arachidonic acid derivatives formed by the action of lipoxygenases are related to various disease states. Some of these arachidonic acid metabolites have been classified as members of a
The present invention relates to novel derivatives of methylene-diphosphonic acid, possessing therapeutic properties permitting their use in the treatment of inflammation symptoms.
More precisely, the compounds according to the invention correspond to the general formula: ##STR4## where: R.sub.1 is