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Introduction Cardiovascular (CV) disease is a major cause of premature death and morbidity worldwide. It is widely known that age, sex, hypertension, dyslipidemia, diabetes, and smoking are the main risk factors which can cause CV disease[1]. Many other CV risk factors and their markers have been
This is a 12-week prospective study with two phases. In Phase 1 (Weeks 1-4), participants will self-monitor their blood pressure using the Qardio bluetooth device. In Phase 2 (Weeks 5-12), the investigators will implement the auto-messaging system triggered by a weekly average systolic blood
Cardiovascular Disease (CVD) is the primary non-communicable cause of global mortality killing more than 7 million people per year. Chronic inflammation plays a crucial role in the genesis of atherosclerosis which further leads to cardiovascular disease. Apical periodontitis is "an acute or chronic
INTRODUCTION Cardiovascular morbidity and kidney impairment Patients with chronic kidney disease (CKD) have a high risk of cardiovascular events and that is already substantial in early stages of CKD. The pathophysiology of cardiovascular disease in CKD patients is poorly understood. In end stage
Introduction
National and International significance of the research
According to a worldwide estimate 42% of people with coronary artery disease (CAD) are physically inactive. There are approximately 200 000 persons in Finland with CAD, and even more have other connected health problems (high
Although the immune system is essential to survival, a variety of diseases originate from inappropriate or excessive activation of the immune response. Examples include a wide range of auto-inflammatory disease, infectious diseases such as sepsis, but also after major surgery like cardiac artery
Stroke is a leading cause of death worldwide, and is a prominent cause of chronic disability, causing significant physical, cognitive and social impairment. In the United Kingdom, there are 150,000 strokes each year, with ~900,000 people living with the debilitating effects of stroke.Individuals who
A two-arm cross-over clinical study with a diet control will be assessed at the Catholic University of Murcia (UCAM).
A recruitment of 50 volunteers will be attempted in order to fulfil the UCC calculations. The 50 patients will be divided into two groups (25 vs 25). One group will receive dry-cured
In animal studies, the mineralocorticoid receptor antagonist eplerenone appears to limit myocardial infarct size. This cardioprotective effect might explain, at least in part, the beneficial effect on mortality of eplerenone in patients with heart failure. Previous animal studies suggest that this
Ischemic Preconditioning (IPC) refers to the phenomenon where a brief ischemia-reperfusion event to a tissue/organ can result in subsequent protection from a more severe ischemia-reperfusion event to that tissue/organ. There are many descriptions of IPC in animal models. Protection occurs in two
The hypothesis for this study was that Regadenoson will produce a very similar degree of maximal hyperemia (increased blood flow) as adenosine, the other vasodilator agent. There were only 2 days on study for each subject.
On Day 1 of the study, subjects were interviewed and had a physical exam,
Objectives To determine the effects of exercise training on insulin resistance in CAD subjects without diabetes, independent of changes in weight, diet, or the effect of acute exercise.
The study was approved by the Research Ethics Review Boards at London and Hamilton. All participants provided
Objective: (i) To identify the differences between the "intervention" and "usual care" groups in Framingham risk scores, anthropometrical, biochemical parameters at baseline and at 24 months and compliance to prescribed regimens. Prevalence of maternal and paternal risk factors, DNA/mRNA profile and