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Caffeine-induced contraction in arteries from stroke-prone spontaneously hypertensive rats.
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Differences in caffeine-induced contraction in smooth muscle of resistance vessels from stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar Kyoto rats (WKY) were investigated by using mesenteric artery preparations. The contraction induced by caffeine (10 mM) was greater in SHRSP
Reduced effect of caffeine on twitch contraction of oesophageal striated muscle from stroke-prone spontaneously hypertensive rats.
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1. There are known differences in the sensitivity to caffeine between skeletal muscle (soleus) of normotensive Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). The present study was performed in order to examine differences in the effects of caffeine on twitch contraction between
Ethanol plus caffeine (caffeinol) for treatment of ischemic stroke: preclinical experience.
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OBJECTIVE
Ethanol and caffeine are 2 common psychoactive dietary components. We have recently shown that low-dose ethanol plus caffeine results in a 70% to 80% reduction of infarct volume after reversible common carotid/middle cerebral artery (CCA/MCA) occlusion in rats. The combination (caffeinol)
Caffeine reduces cerebral blood flow in patients recovering from an ischaemic stroke.
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BACKGROUND
Caffeine is present in a variety of beverages and food and is widely consumed. In a previous study of patients recovering from an acute ischaemic stroke using transcranial Doppler ultrasound we demonstrated a fall in middle cerebral artery blood velocity of 12% following ingestion of 250
Pilot dose-escalation study of caffeine plus ethanol (caffeinol) in acute ischemic stroke.
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OBJECTIVE
In animal models, the combination of caffeine and ethanol (caffeinol) provides robust neuroprotection at blood levels that should be easily and safely achieved in humans. This study was designed to determine the safety and tolerability of ascending doses of this combination in stroke
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
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BACKGROUND
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region.
OBJECTIVE
The objective of this review was to assess the effect of theophylline and its analogues
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.
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BACKGROUND
Theophylline causes potent cerebral vasoconstriction which decreases blood flow in the non-ischaemic areas of the brain and increases collateral blood flow surrounding the ischaemic region. NOTE: This review covers an area where no active research is taking place. It will be updated if
Influence of combined administration of ethyl alcohol with caffeine and hydroxyzine on cardiac minute volume and stroke volume in rabbits.
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The effect of combined administration of ethyl alcohol with caffeine and hydroxyzine on cardiac volume and vascular resistance was studied. Combined administration of these compounds diminished cardiac stroke volume and minute output and increased general vascular resistance. Simultaneous
Measuring caffeine-induced changes in middle cerebral artery blood velocity using transcranial Doppler in patients recovering from ischaemic stroke.
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Acute ingestion of caffeine is known to reduce cerebral blood flow in normal volunteers and in certain patient groups. There is no evidence that this causes problems in the normal population. However, there may be implications if a similar reduction occurs in patients recovering from an ischaemic
Intranasal caffeine and amphetamine causing stroke.
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A 37 year-old man with an ischaemic stroke after the nasal use of amphetamine and caffeine is reported. Transient arterial hypertension due to these agents may have been the mediator of the stroke. Mitral annular calcification was the only other abnormality found, and was thought not to play an
Unaltered caffeine-induced relaxation in the aorta of stroke-prone spontaneously hypertensive rats (SHRSP).
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Caffeine-induced relaxation was studied in aortic segments from Wistar Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP). Although acetylcholine-induced endothelium-dependent relaxation was impaired in preparations from SHRSP, the relaxation induced by caffeine was identical
Usual dose of caffeine has a positive effect on somatosensory related postural stability in hemiparetic stroke patients.
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OBJECTIVE
To evaluate the effect of caffeine on balance control of hemiparetic stroke patients, we investigated the difference in postural stability before and after drinking coffee by observing changes in stability index (SI) from posturography.
METHODS
Thirty patients with history of stroke and 15
Caffeine-containing medicines increase the risk of hemorrhagic stroke.
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OBJECTIVE
Research on the relationship between caffeine-containing medicines (CCMs) and the risk of hemorrhagic stroke (HS) is sparse. The aim of this study is to evaluate the association between CCMs and the risk of HS.
METHODS
We performed a multicenter case-control study in South Korea, from 2002
Refractory caffeine and ergot-induced cervico-cerebral vasospasm and stroke treated with combined medical and endovascular approach.
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Caffeine and stroke.
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