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6 hasil
Inhibition of nuclear transcription factor NF-.kappa.B by caffeic acid phenethyl ester (CAPE), derivatives of CAPE, capsaicin (8-methyl-N-vanillyl-6-nonenamide) and resiniferatoxin
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates generally to inhibitors of nuclear transcription factor NF-.kappa.B, and the use of these inhibitors in the treatment of pathological conditions in humans. Specifically, the present invention relates to the
Anti-tumor pharmaceutical composition comprising N-vanillyl fatty acid amide
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FIELD OF THE INVENTION
The present invention relates to an anti-tumor pharmaceutical composition. In particular, the present invention relates to an anti-tumor pharmaceutical composition having an antiproliferative effect on melanoma cells and leukemia cells.
BACKGROUND OF THE INVENTION
Recently,
Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
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1. INTRODUCTION
The present invention relates to novel methods and compositions which utilize catechins, including but not limited to, epigallocatechin gallate (EGCg), epicatechin (EC), epicatechin gallate (ECG), and epigallocatechin (EGC), which are found in varying levels in tea leaves, in
Capsacinoid compounds as proliferation inhibitors
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TECHNICAL FIELD
The field of this invention is the treatment of neoplasia.
BACKGROUND
Cancer has been one of the major plagues of society. Cancer appears to be a result of genetic defects, aging, viral infections, exposure to mutagens, and may have other causative events. The uncontrolled
2-aminobenzamide derivatives
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TECHNICAL FIELD
The present invention relates to a pharmaceutical, particularly a novel 2-aminobenzamide derivative or a salt thereof useful as an inhibitor for the capsaicin receptor VR1 (Vanilloid Receptor 1) activation, and a pharmaceutical thereof.
BACKGROUND OF THE INVENTION
VR1 is a receptor
Application of lipid vehicles and use for drug delivery
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FIELD OF THE INVENTION
The present invention relates to compositions and methods for the Instillation of lipid vehicles (e.g., micelles, microemulsions, macroemulsions, and liposomes) to treat various disorders, including bladder inflammation and dysfunction. The vehicles of the present invention
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