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Amtolmetin Gaucil in Knee Osteoarthritis

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Osteoarthritis is the most common rheumatic disease. Knee OA (KOA), gonarthrosis (GA), is characterized by high prevalence, progressive course with early disability of the subject, persistent pain syndrome for the treatment of which non-steroidal anti inflammatory drugs (NSAIDs) are actively used in

Therapeutic Equivalence Between Branded and Generic WARFArin Tablets in Brazil

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[Changes to the protocol made until the stage of the statistical analysis plan, before data analysis and also before unblinding.] 1. Objective 1.1 Main Objective We aim to determine, through mean INR difference between formulations, whether there is therapeutic equivalency between the branded

Analgesic Effect of Oxytocin Receptor Modulation

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Background Chronic pain is still a largely unresolved issue, causing suffering, disability and high social costs. The search for novel pharmacological targets is therefore a priority. A recent study on postpartal bleeding came to the accidental finding of a possible analgesic action of the oxytocin

Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash

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Mucositis Mucositis is an adverse effect as a result of chemotherapy and radiation treatments and has significant quality of life and clinical consequences. Mucositis is a result of direct cytotoxic damage as well as a cytokine-mediated inflammatory response and can affect the epithelial mucosal

Evaluation of the Antipruritic Effect of Elidel (Pimecrolimus) in Non-atopic Pruritic Disease

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Patients will be treated with pimecrolimus cream 1% and hydrocortisone cream 1% twice daily for 8 weeks on diseased skin in a double-blind, randomized within patient comparison (left arm pimecrolimus, right arm hydrocortisone or vice versa). Patients will then enter a 4-week treatment free follow-up
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