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BACKGROUND OF THE INVENTION
Capsaicin is a chemical isolated from the fruits of plants of the nightshade family, principally the pepper plant. It requires processing of about 10,000 pounds of peppers to extract a yield of 1 pound of capsaicin. Capsaicin has in recent years been used topically on the
BACKGROUND OF THE INVENTION
Capsaicin is a chemical isolated from the fruits of plants of the nightshade family, principally the pepper plant. It requires processing of about 10,000 pounds of peppers to extract a yield of 1 pound of capsaicin. Capsaicin has in recent years been used topically on the
FIELD OF THE INVENTION
This invention relates to a method of treatment of migraine headaches. More particularly, it relates to the treatment of stress-induced migraine headaches with agents that inhibit the action or actions of the neuroendocrine polypeptide, corticotropin releasing
CROSS REFERENCE TO RELATED APPLICATION
This application is a 371 of PCT/JP04/008479, filed on Jun. 10, 2004, and claims priority to the following applications: Japanese Patent Application No. 2003-167865, filed on Jun. 12, 2003 and Japanese Patent Application No. 2003-405086, filed on Dec. 3,
TECHNICAL FIELDS
The present invention relates to novel benzamide derivatives or salts thereof useful as medicaments, particularly, capsaicin receptor VR1 (Vanilloid Receptor 1) activation inhibitor, and the medicaments.
BACKGROUND ART
Capsaicin, which is a main component of chili pepper, is an
TECHNICAL FIELD
The present invention relates to a pharmaceutical, particularly a novel 2-aminobenzamide derivative or a salt thereof useful as an inhibitor for the capsaicin receptor VR1 (Vanilloid Receptor 1) activation, and a pharmaceutical thereof.
BACKGROUND OF THE INVENTION
VR1 is a receptor