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Cytotoxic coumaronochromones from the inflorescences of Celosia cristata.
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Investigation on the MeOH extracts of the inflorescences of Celosia cristata led to the isolation of two new coumaronochromones, cristatone I (1) and cristatone II (2), along with three known flavones (3-5). Their structures were elucidated on the basis of spectroscopic analyses. Compounds 1-5 were
Characterization of Anticancer Principles of Celosia argentea (Amaranthaceae).
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BACKGROUND
An Indian origin, Celosia argentea is a weed growing during rainy season traditionally claimed for treating several ailments. Early researches on C. argentea were focused on the anti-cancer screening of seeds, with few reports on aerial parts.
OBJECTIVE
To isolate and characterize
A pair of cyclopeptide epimers from the seeds of Celosia argentea.
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Two cyclopeptides, celogentin L (1) and its epimer lyciumin A (2) were firstly isolated from Celosia argentea L.. The planar structures of the two compounds were fully determined by spectroscopic data, including 1D-, 2D-NMR, and HR-ESI/MS. The absolute configurations of amino acid components were
Immunostimulating activity of Celosian, an antihepatotoxic polysaccharide isolated from Celosia argentea.
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Celosian, an acidic polysaccharide from the seeds of Celosia argenteo (Amaranthaceae) was found to be a potent antihepatotoxic agent for chemical and immunological liver injury models in animals. The immunomodulating action of celosian was studied to clarify the preventive mechanism of celosian on
Purification, characterization and immunomodulatory activity of a polysaccharide from Celosia cristata.
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A polysaccharide CP1-1 was isolated and purified from Celosia cristata. Its average molecular weight was 2.3kDa and it was composed of glucose and galactose in a ratio of 1.00:2.03, and traces of mannose. Chemical characterization of CP1-1 was elucidated by methylation analysis. CP1-1 was a branched
Anti-neuroinflammatory effect of Iresine celosia on lipopolysaccharide-stimulated microglial cells and mouse.
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Abnormal inflammatory response in the central nervous system plays a critical role in various neurological disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease. Therefore, modulation of abnormal neuroinflammation is thought to be a promising therapeutic strategy for
Anti-metastatic and immunomodulating properties of the water extract from Celosia argentea seeds.
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We have investigated the anti-metastatic effect of Celosia argentea seed extracts (CAE), which have traditionally been used as a therapeutic drug for eye and hepatic diseases in China and Japan. Intraperitoneal (i.p.) administration of CAE for 7 d before tumor inoculation significantly inhibited
Production of dihydroxylated betalains and dopamine in cell suspension cultures of Celosia argentea var. plumosa.
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Betalains are plant pigments of hydrophilic nature with demonstrated chemopreventive potential in cancer cell lines and animal models. Among the betalains, those containing an aromatic moiety with two free hydroxyl groups possess the strongest antioxidant and free radical scavenging activities. The
Cytotoxic activity of selected Nigerian plants.
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Cancer is one of the most prominent human diseases which has stimulated scientific and commercial interest in the discovery of new anticancer agents from natural sources. The current study investigates the cytotoxic activity of ethanolic extracts of sixteen Nigerian plants used locally for the
Protective effect of celosian, an acidic polysaccharide, on chemically and immunologically induced liver injuries.
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Hepatoprotective effect of celosian, an acidic polysaccharide isolated from the water extract of the seed of Celosia argentea, was investigated using chemical and immunological liver injury models. Celosian inhibited the elevation of serum enzyme (GPT, GOT, LDH) and bilirubin levels on carbon
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