clausena excavata/glutathione

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Antihypertensive and vasoprotective effects of Clausena lansium fruits extract in L-NAME induced hypertensive rats

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Oxidative stress is considered to play an important role in the pathophysiology of hypertension. The aim of this research was to find out whether Clausena lansium (Lour.) Skeels of Wampee (WP) fruits extract attenuate the progression of high blood pressure, endothelial dysfunction and preservation

Structure-activity relationship in the toxicity of some naturally occurring coumarins-chalepin, imperatorin and oxypeucedanine.

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Imperatorin, oxypeucedanine and chalepin are furanocoumarins isolated from Clausena anisata a medicinal plant common in West Africa. Only chalepin is found to have anticoagulant activity when administered to rats at a single dose. Aniline hydroxylase activity was appreciably depressed by each of the

Prophylactic effects of Clausena excavata Burum. f. leaf extract in ethanol-induced gastric ulcers.

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Clausena excavata is a natural herb with both antioxidant and anti-inflammatory properties. It has been used for decades in folkloric practice for the amelioration of various ailments. In this study, the gastroprotective activity of methanolic extract of C. excavata leaves (MECE) was determined in

Physicochemical properties and antioxidant activities of acidic polysaccharides from wampee seeds.

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Two novel polysaccharide fractions, named WP1 and WP3, were extracted and purified from wampee [Clausena lansium (Lour.) Skeels] seeds. Their physicochemical properties, in vitro and in vivo antioxidant activities were investigated. Results indicated that both WP1 and WP3 were acidic

(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis

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Drug-induced liver injury is the major cause of acute liver failure. However, the underlying mechanisms seem to be multifaceted and remain poorly understood, resulting in few effective therapies. Here, we report a novel mechanism that contributes to acetaminophen-induced hepatotoxicity through the

Anti-ulcerogenic activity of dentatin from clausena excavata Burm.f. against ethanol-induced gastric ulcer in rats: Possible role of mucus and anti-oxidant effect.

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Clausena excavata Burm.f. (Rutaceae) has been used for the treatment of stomach disorders including peptic ulcer.In this study, we aimed to investigate dentatin isolated from C. excavata Burm.f., for anti-ulcer activity against ethanol ulcer model in

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