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combretum apiculatum/pendarahan
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Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate.
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The combretastatins are derived from an African medicinal plant Combretum caffrum (Combretaceae). They have previously been shown to be potent inhibitors of microtubule assembly that cause marked haemorrhagic necrosis in murine subcutaneous tumors. Promising clinical trial results with
Counteraction of Bothrops snake venoms by Combretum leprosum root extract and arjunolic acid.
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BACKGROUND
Serotherapy against snakebite is often unavailable in some regions over Brazil, where people make use of plants from folk medicine to deal with ophidic accidents. About 10% of Combretum species have some ethnopharmacological use, including treatment of snakebites.
METHODS
We evaluated the
Bioactivities of the genus Combretum (Combretaceae): a review.
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The Combretaceae is a large family of herbs, shrubs and trees, comprising about 20 genera and 600 species with tropical distribution around the globe and centers of diversity in Africa and Asia. Some Combretum species are extensively used in traditional medicine against inflammation, infections,
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