coronary artery disease/scopolamine

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Effect of transdermal scopolamine on heart rate variability in patients with severe coronary heart disease.

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A decrease in cardiac parasympathetic tone is a recognized finding in patients with ischemic heart disease, correlating closely with disease severity and overall survival. The aim of this study was to assess whether transdermal scopolamine (Tds), which increases parasympathetic tone in healthy

Acute complete heart block during anesthesia in a patient with severe coronary artery disease: effect of scopolamine versus ischemia of the AV node.

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Double blind placebo controlled trial of short term transdermal scopolamine on heart rate variability in patients with chronic heart failure.

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OBJECTIVE To test the hypothesis that short term application of transdermal scopolamine increases heart rate variability (HRV) and restores sympathovagal balance in patients with stable congestive heart failure (CHF). METHODS A double blind placebo controlled crossover study. METHODS Tertiary

Comparison of the effects of 15 and 60 micrograms/kg fentanyl used for induction of anesthesia in patients with coronary artery disease.

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We compared the effects of 15 and 60 micrograms/kg fentanyl used for induction in 40 patients, 50-72 yr old, with coronary artery disease and mildly impaired ventricular contractility. Morphine (0.1 mg/kg) and scopolamine (0.4 mg) were used for premedication. Crystalloid (500 ml) was administered

Hemodynamic effects of diazepam and diazepam-nitrous oxide in patients with coronary artery disease.

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Circulatory responses following intravenous diazepam (0.5 mg/kg) and the subsequent addition of 50% nitrous oxide were studied in 14 patients undergoing elective aortocoronary saphenous vein bypass operations. No patient was receiving propranolol. Preanesthetic medication was with morphine and

Arterial hypoxaemia following premedication in patients with coronary artery disease.

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The effect of premedication with morphine and scopolamine, morphine alone, and scopolamine alone on arterial oxygen tension has been studied in patients with coronary artery disease undergoing bypass operations. Control arterial blood samples were obtained with the patients in the supine position

Effects of transdermal scopolamine on heart rate variability in normal subjects.

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A decrease in cardiac parasympathetic tone is a recognized finding in patients with ischemic heart disease, sudden cardiac death and heart failure, correlating closely with disease severity and overall survival. To study the clinical potential of vagomimetic intervention, the effect of transdermal

Circulatory effects of isoflurane in patients with ischemic heart disease: a comparison with halothane.

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The circulatory effects of isoflurane (I) were compared with those of halothane (H) in two groups of patients premedicated with morphine and scopolamine and scheduled for coronary artery bypass surgery. Both groups were similar with respect to age, weight, sex distribution, body surface area, left

Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade.

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Experimental and clinical evidence documents the beneficial effects of blocking sympathetic activity and modulating heart rate to reduce risk for lethal events in ischemic heart disease. Beside beta-adrenergic receptor blockade, vagal activation is a meaningful approach but not yet easily

[Syncope - a systematic overview of classification, pathogenesis, diagnosis and management].

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Syncope is defined as a temporary interruption of cerebral perfusion with a sudden and transient loss of consciousness and spontaneous recovery. Approximately one third of the population experiences syncope at least once during a lifetime. Presyncopal signs and symptoms, including weakness,

Hemodynamic changes during fentanyl--oxygen anesthesia for aortocoronary bypass operation.

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Fentanyl in doses of 50-60 microgram/kg has been reported to produce anesthesia with remarkable hemodynamic stability in patients with coronary artery disease (CAD). Because the authors had observed hypertension and tachycardia in response to noxious stimulation during aortocoronary bypass (ACB)

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