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coronary artery disease/triglyceride
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Method for stimulating weight loss and/or for lowering triglycerides in patients
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BACKGROUND OF THE INVENTION AND DISCUSSION OF THE PRIOR ART
Researchers at the Centers for Disease Control and Prevention (CDC) estimated that as many as 47 million Americans may exhibit a cluster of medical conditions (a "metabolic syndrome") characterized by abdominal obesity,
Procedure for the determination of triglyceride contained in low density lipoprotein
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The present invention relates to a procedure or a diagnostic product for the determination of triglyceride contained in lipoprotein.
Coronary heart disease (CHD) is still the main cause of death in the Western industrial nations. While the importance of cholesterol as a risk factor for coronary
Amide inhibitors of microsomal triglyceride transfer protein
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FIELD OF THE INVENTION
The present invention relates to compounds that are inhibitors of the microsomal triglyceride transfer protein. The invention also relates to methods of treatment of atherosclerosis, obesity, restenosis, coronary heart disease, hyperlipoproteinemia, hypercholesterolemia, and
Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism
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DESCRIPTION
This invention relates to the use of nucleic acid sequences of the MAP kinase-interacting kinase (Mnk) gene family and amino acid sequences encoded thereby, and to the use of these sequences or effectors of Mnk nucleic acids or polypeptides, particularly Mnk kinase inhibitors and
Protein disulfide isomerase and ABC transporter homologous proteins involved in the regulation of energy homeostasis
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority to PCT Patent Application No. PCT/EP02/03540 filed Mar. 28, 2002 and European Patent Applications No. EP01 108 315.1 filed Apr. 2, 2001 and EP01 113 419.4 filed Jun. 1, 2001.
DESCRIPTION
This invention relates to the use of
Protein disulfide isomerase and ABC transporter homologous proteins involved in the regulation of energy homeostasis
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DESCRIPTION
This invention relates to the use of nucleic acid and amino acid sequences of protein disulfide isomerase and ABC transporter homologous proteins, and to the use of these sequences in the diagnosis, study, prevention, and treatment of diseases and disorders related to body-weight
4-((substituted phenyl) difluoromethyl) phenoxy carboxylic acid derivative, and preparation method and uses thereof
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CROSS-REFERENCE TO RELATED APPLICATIONS
The present application is a national phase entry under 35 U.S.C. .sctn.371 of International Application No. PCT/CN2013/074739, filed on Apr. 25, 2013, published in Chinese, which claims priority from Chinese Patent Application No. 201210125154.4, filed Apr.
Azolopyridin-2-one derivatives as lipase and phospholipase inhibitors
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The present invention relates to azolopyridin-2-one derivatives of the general formula I, to their pharmaceutically useful salts and to their use as medicinal substances.
Compounds of similar structure are known from EP 1275653. However, these are used as fungicides.
Compounds having an inhibitory
Method, reagent and kit for evaluating susceptibility to premature atherosclerosis
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BACKGROUND OF THE INVENTION
This application relates to a method, reagent and kit for evaluating susceptibility to and causation of premature atherosclerosis and other forms of coronary artery disease. The invention further relates to a method of gene therapy by which lipoprotein lipase deficiencies
Gene therapy method for reducing risk of atherosclerosis
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BACKGROUND OF THE INVENTION
This application relates to a method, reagent and kit for evaluating susceptibility to and causation of premature atherosclerosis and other forms of coronary artery disease. The invention further relates to a method of gene therapy by which lipoprotein lipase deficiencies
Heterocyclic analogs of diphenylethylene compounds
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BACKGROUND OF THE INVENTION
The present application is directed to novel compounds formed by chemically coupling diphenylethylene compounds and derivatives thereof with thiazolidine or oxazolidine intermediates. These compounds are effective for providing a variety of useful pharmacological effects.
Heterocyclic analogs of diphenylethylene compounds
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BACKGROUND OF THE INVENTION
The present application is directed to novel compounds formed by chemically coupling diphenylethylene compounds and derivatives thereof with thiazolidine or oxazolidine intermediates. These compounds are effective for providing a variety of useful pharmacological effects.
Heterocyclic analogs of diphenylethylene compounds
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BACKGROUND OF THE INVENTION
The present application is directed to novel compounds formed by chemically coupling diphenylethylene compounds and derivatives thereof with thiazolidine or oxazolidine intermediates. These compounds are effective for providing a variety of useful pharmacological effects.
Heterocyclic analogs of diphenylethylene compounds
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BACKGROUND OF THE INVENTION
The present application is directed to novel compounds formed by chemically coupling diphenylethylene compounds and derivatives thereof with thiazolidine or oxazolidine intermediates. These compounds are effective for providing a variety of useful pharmacological effects.
Combinations of botanical extracts for promoting cardiovascular health
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FIELD OF THE INVENTION
The present invention relates to medicinal compositions, particularly to combinations of botanical extracts for promoting cardiovascular health.
BACKGROUND OF THE INVENTION
Cardiovascular disease (CVD), including coronary heart disease, atherosclerosis, stroke, myocardial
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