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13 hasil
Tonic convulsions induced in mice by vaccinia virus and their prevention by heated influenza virus.
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One year of EEG unit at psychiatric hospital, Yaba, Lagos.
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To show the continuous investigative value of electroencephalography (EEG) in the management of neuro-pathological disorders such as epilepsy in Nigeria. The limitation against this, especially lack of adequate fund to procure the EEG machine was highlighted. A prospective study over the first
Vaccinia virus variants as presumable cause of vaccinial complications.
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Two vaccinia viruses isolated from patients with vaccinial complications (vaccinial ulcer, postvaccinial seizures) showed qualitative differences from the original parental strain. After intradermal injection of the viruses into the rabbit marked necroses developed, which the original strains did
Safety and biodistribution of a double-deleted oncolytic vaccinia virus encoding CD40 ligand in laboratory Beagles.
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We evaluated adverse events, biodistribution and shedding of oncolytic vaccinia virus encoding CD40 ligand in two Beagles, in preparation for a phase 1 trial in canine cancer patients. Dog 1 received one dose of vaccinia virus and was euthanized 24 hours afterwards, while dog 2 received virus four
Clinical neuropsychiatric correlates and EEG findings among children with developmental disorders in Lagos, Nigeria.
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OBJECTIVE
Developmental disorders with or without associated neuropsychiatric complications continue to be one of the major health problems in Africa. The grossly inadequate management/ rehabilitative facilities further worsen this. A prospective study aimed at finding the types of developmental
Postvaccinal encephalomyelitis without cutaneous vaccination reaction.
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A 5-year-old girl developed a progressive febrile neurological illness consisting of right focal seizures, right hemiparesis, and stupor evolving over a period of six weeks. During the month preceding the onset of her illness she had received two apparently unsuccessful smallpox vaccinations without
Smallpox vaccination and adverse reactions. Guidance for clinicians.
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The guidance in this report is for evaluation and treatment of patients with complications from smallpox vaccination in the preoutbreak setting. Information is also included related to reporting adverse events and seeking specialized consultation and therapies for these events. The frequencies of
Long stay patients in a psychiatric hospital in Lagos, Nigeria.
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OBJECTIVE
In the face of recently introduced government health reform and the dwindling number of available beds for acutely ill patients, a cross sectional study was carried out on long-stay patients at the 100 years old psychiatric hospital Yaba, Lagos, Nigeria with a view to discharging most of
[Central activity, antihypertensive action and antiulcerogenic effects of neurotropin].
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Central activity, antihypertensive action and antiulcerogenic actions of Neurotropin (NSP), an extract isolated from vaccinia virus-innoculated skin or tissues of rabbits were investigated herein. When actions of NSP were examined in isolated muscle preparations by the Magnus-method, peristalsis and
Disease versus disease: how one disease may ameliorate another.
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Systemic disease, either genetic or acquired, may prevent or decrease the severity of another disease. These observations have led to important therapeutic advances. The best-known examples are Edward Jenner's use in 1798 of cowpox to prevent smallpox and J.B. Haldane's 1942 observation that
Recent trends of drug abuse and drug-associated deaths in Korea.
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Methamphetamine is the most abused drug in Korea followed by cannabis and opiates. Recent characteristics of the drug problem in Korea include increased drug smuggling from abroad, drug trafficking by organized gangs, varieties of drug smuggling, foreigners engaged in drug smuggling, and spread
Substance Abuse and the HIV Situation in Malaysia.
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Heroin continues to be the main drug used in Malaysia, while amphetamine-type stimulants (ATS) have been recently identified as a growing problem. A cumulative total of 300,241 drug users were detected between 1988 and 2006. It is also estimated that Malaysia has 170,000 injecting drug users. HIV
Classification, diagnosis and potential mechanisms in pontocerebellar hypoplasia.
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Pontocerebellar Hypoplasia (PCH) is group of very rare, inherited progressive neurodegenerative disorders with prenatal onset. Up to now seven different subtypes have been reported (PCH1-7). The incidence of each subtype is unknown. All subtypes share common characteristics, including
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