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BACKGROUND OF THE INVENTION
1. Technical Field of the Invention
This invention relates generally to cytoenzymology, and more particularly to methods and reagents used in cytoenzymology.
2. Discussion of the Background Art
Apoptosis, or programmed cell death, is a process that involves the activation
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The present invention relates to recombinant proteins and their use.
Tumour necrosis factor-.alpha. (TNF.alpha.) is a potent cytokine which elicits a broad spectrum of biological responses. TNF.alpha. causes the cytolysis or cytostasis of many tumour cell lines in vitro, induces the haemorrhagic
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BACKGROUND OF THE INVENTION
Cellular interactions which occur during an immune response are regulated by members of several families of cell surface receptors, including the tumor necrosis factor receptor (TNFR) family. The TNFR family consists of a number of integral membrane glycoprotein receptors
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BACKGROUND OF THE INVENTION
Cellular interactions which occur during an immune response are regulated by members of several families of cell surface receptors, including the tumor necrosis factor receptor (TNFR) family. The TNFR family consists of a number of integral membrane glycoprotein receptors
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FIELD OF THE INVENTION
The present invention relates to ligands to Tumor Necrosis Factor receptors (TNF-Rs) which inhibit the effect of TNF but not its binding to the TNF-Rs, as well as to ligands interacting with other receptors of the TNF/NGF family.
BACKGROUND OF THE INVENTION
Tumor necrosis
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FIELD OF THE INVENTION
The present invention relates to ligands to Tumor Necrosis Factor receptors (TNF-Rs) which inhibit the effect of TNF but not its binding to the TNF-Rs, as well as to ligands interacting with other receptors of the TNF/NGF receptor family.
BACKGROUND OF THE INVENTION
Tumor
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TECHNICAL FIELD
The invention relates to polypeptides that include a binding site for immunoregulatory molecule B-T lymphocyte attenuator (BTLA). Furthermore, the invention relates to ligands, such as antibodies, that bind to a binding site for immunoregulatory molecule B-T lymphocyte attenuator
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FIELD OF THE INVENTION
The present invention relates to ligands to Tumor Necrosis Factor receptors (TNF-Rs) which inhibit the effect of TNF but not its binding to the TNF-Rs, as well as to ligands interacting with other receptors of the TNF/NGF family.
BACKGROUND OF THE INVENTION
Tumor necrosis
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FIELD OF THE INVENTION
The present invention relates to ligands to Tumor Necrosis Factor receptors (TNF-Rs) which inhibit the effect of TNF but not its binding to the TNF-Rs, as well as to ligands interacting with other receptors of the TNF/NGF family.
BACKGROUND OF THE INVENTION
Tumor necrosis
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The present invention relates to a cyclic protein free from cysteines which can be used as a medicament, e.g., for activating epithelial ion channels, for improving the lung function as well as for treating oedemas such as pulmonary oedemas.
The fluid transport through cell layers and tissue is
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