Diabetic retinopathy / obesitas

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazole derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic disorders

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazol-2-ium derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

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FIELD OF THE INVENTION The present invention provides novel 1,2,4-thiadiazole derivatives useful for the treatment of a disorder mediated by a melanocortin receptor. More particularly, the compounds of the present invention are useful for the treatment of metabolic, CNS and dermatologic disorders

Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein

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ANGIOGENESIS In an adult, two types of blood vessels can potentially be found. The normal blood vessel is a resting, quiescent, fully developed vessel. A second form, a proliferating or developing blood vessel, occurs rarely during the normal human life cycle (occurring only in early development and

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Synthesis of 3,3,4,4-tetrafluoropyrrolidine and novel dipeptidyl peptidase-IV inhibitor compounds

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FIELD OF INVENTION The present invention relates to a method of making novel dipeptidyl peptidase-IV ("DPP-IV`) inhibitor compounds and a method of making 3,3,4,4-tetrafluoropyrrolidine, a starting material utilized in the afore-mentioned method for preparing DPP-IV compounds. BACKGROUND OF

Benzene compounds

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to benzene compounds, and more particularly, to novel benzene compounds having inhibition activity on acetyl CoA carboxylase ("ACC" hereinafter). 2. Discussion of the Background It has become clear in recent years

Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids

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FIELD OF THE INVENTION The present invention concerns the preparation and uses of adamantanamines (e.g. memantine, amantadine and rimantadine) and neramexane(s) salts of thiomolybdic acids and thiotungstic acids. Their pharmaceutical compositions incorporate two complementary, bioavailable

Lactam compound, a method for producing the same, and a diabetic therapy by administering the same

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medicinal drug, and in particular, to a novel lactam compound having sugar transport enhancement action and having excellent hypoglycemic action, a preparation method thereof, and a preparation intermediate

Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is directed to inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment

Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is directed to inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment

diabetic retinopathy/obesitas

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

1,2,4-thiadiazolium derivatives as melanocortin receptor modulators

1,2,4-thiadiazole derivatives as melanocortin receptor modulators

Inhibition of angiogenesis and destruction of angiogenic vessels by apolipoprotein A-I and high density lipoprotein

Indolylmaleimide derivatives

Indolylmaleimide derivatives

Indolylmaleimide derivatives

Synthesis of 3,3,4,4-tetrafluoropyrrolidine and novel dipeptidyl peptidase-IV inhibitor compounds

Benzene compounds

Adamantanamines and neramexane salts of thiomolybdic and thiotungstic acids

Lactam compound, a method for producing the same, and a diabetic therapy by administering the same

Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity

Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity

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