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dioscorea esculenta/anti alergi
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Anti-allergic substances from the rhizomes of Dioscorea membranacea.
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Extracts of five species of Thai medicinal plants, locally known as Hua-Khao-Yen, were screened for anti-allergic activities using RBL-2H3 cells. Of the five species studied, the ethanolic extract of Dioscorea membranacea exhibited potent inhibitory activity against beta-hexosaminidase release as a
Glycoprotein isolated from Dioscorea batatas Decne modulates expressions of IL-4 and IL-10 in primary-cultured mouse lymphocytes.
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In the present study, we investigated the anti-allergic activity of a glycoprotein isolated from Dioscorea batatas Decne (DBD glycoprotein, 30 kDa) on ovalbumin (OVA, 100 microg ml(-1))-induced T helper (Th) type-2 response in primary cultured mouse lymphocytes. Our results revealed that the DBD
Oral administration with diosgenin enhances the induction of intestinal T helper 1-like regulatory T cells in a murine model of food allergy.
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Although the development of T helper (Th)1-like regulatory T (Treg) cells under Th1 inflammatory conditions has been reported, the role of Th1-like Treg cells in Th2 allergic responses remains mostly unclear. We previously demonstrated that diosgenin, the major sapogenin contained in the Chinese
Class A dioscorins of various yam species suppress ovalbumin-induced allergic reactions.
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BACKGROUND
Dioscorins, the primary storage proteins in yam tubers, of different species exhibited varying immunomodulatory activities in mice. We inferred that this might be attributed to the various isoforms in the yam tubers.
OBJECTIVE
We aimed to investigate the antiallergic potential of the
Suppression of allergic reactions in ovalbumin-sensitized mice by yam storage proteins dioscorins.
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To study the biomedical functions of dioscorins isolated from various species of Dioscorea , we investigated their antiallergic potential using an OVA-induced allergy mouse model. All the dioscorins suppressed allergic reactions by decreasing the serum IgE and histamine levels. The serum IFN-γ and
Diosgenin attenuates allergen-induced intestinal inflammation and IgE production in a murine model of food allergy.
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Diosgenin, the major sapogenin contained in the Chinese yam, has recently been shown to promote systemic T helper 1-type immunity in a murine model of airway hypersensitivity. In this study, we hypothesized that diosgenin might be effective in modulating food allergy. BALB/c mice were either left
Natural phenanthrenes and their biological activity.
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The aim of this review is to survey the various naturally occurring phenanthrene compounds that have been isolated from different plants. Only one review has previously been published on this topic. Gorham (1989) reviewed the structures, biosynthesis, separations and spectroscopy of stilbenes and
Pharmacological Activities of Dehydroepiandrosterone: A Review.
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Dehydroepiandrosterone (DHEA) is a steroidal hormone secreted by Zonareticularis of the adrenal cortex with a characteristic age related pattern of secretion. These hormones are inactive precursors that are transformed into active sex steroids in peripheral target tissues. These hormones are used
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