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Microencapsulated feruloyl esterase-producing lactobacilli ameliorate lipid profile and glycaemia in high fat diet-induced obese mice.
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The effect of oral administration of spray-dried microcapsules of feruloyl esterase (FE) producing Lactobacillus fermentum CRL1446 (Lf) and Lactobacillus johnsonii CRL1231 (Lj) on high fat diet-induced obese mice was investigated to evaluate whether these strains could be used as a biotherapeutic
Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia.
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Increased lipogenesis, together with hyperlipidemia and increased fat deposition, contribute to obesity and associated metabolic disorders including nonalcoholic fatty liver disease. Here we show that carboxylesterase 1/esterase-x (Ces1/Es-x) plays a regulatory role in hepatic fat metabolism in the
Erythrocyte total carbonic anhydrase esterase activity in african american obese children: reduction starts at a young age.
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Lipolytic esterase activity of adipose tissue from mice with three types of hereditary obesity.
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[Effect of mazindol on obesity induced by administration of gold thioglucose].
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The present experiments were carried out to elucidate the effect of mazindol feeding on obese mice made by gold-thioglucose injection. Mazindol was added to the diet at the level of 0.5, 2, 10 mg/kg body weight. It was found that oral administration of mazindol reduced the body weight gain and
Subcutaneous adipose tissue development in Yorkshire (lean) and Ossabaw (obese) pigs.
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Subcutaneous adipose tissue development was studied in Yorkshire (lean) and Ossabaw (obese) pigs. Three pigs of each breed were slaughtered at 1 to 2 (group 1), 14 to 20 (group 2), 56 to 70 (group 3) and 180 (group 4) days of age. Formalin and(or) Bouin's fixed paraffin sections were analyzed by
Techniques for identification of the young obese Zucker rat and some observations on brown adipose tissue morphology and histochemistry in the young obese Zucker rat.
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Several techniques for the identification of the young obese Zucker rat were developed and tested. A procedure utilizing biopsies of hypodermal adipocytes was successful in identifying the obese phenotype in large litters of 7-d and older rats. This technique involves sizing and counting fat cells
Skeletal muscle cellularity and histochemistry in young lean and obese pigs.
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The cellularity and histochemistry of the semitendinosus muscle was studied in lean and obese pigs at 14 days of age. Muscles from lean animals had lower (P less than .05) muscle weights and minimum fiber diameters and had reduced (P less than .05) percentages of dry matter and protein when
Changes in the plantaris muscle as an indicator of alterations in lean body mass of obese Zucker rats following prolonged energy restriction and subsequent partial recovery.
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To study the effects of a prolonged (80 day), severe (64% body mass loss) energy restriction and subsequent refeeding on skeletal muscle tissue, specifically the plantaris muscle, 21 genetically obese Zucker rats were selected for this study. Six rats were initially killed and served as baseline
The effect of weight on the efficacy and safety of C1 esterase inhibitor concentrate for the treatment of acute hereditary angioedema.
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BACKGROUND
Despite the worldwide obesity epidemic, there have been very few studies investigating the influence of body weight on treatment dosing and outcomes in patients with hereditary angioedema (HAE).
OBJECTIVE
The purpose of this analysis was to determine whether the standard weight-based
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Portuguese women.
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BACKGROUND
Obesity became a major public health problem as a result of its increasing prevalence worldwide. Paraoxonase-1 (PON1) is an esterase able to protect membranes and lipoproteins from oxidative modifications. At the PON1 gene, several polymorphisms in the promoter and coding regions have
Expression of nonspecific esterase (NSE) by thyroid follicular epithelium as a marker for the target organ susceptibility to immune system attack.
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Spontaneous autoimmune thyroiditis in obese strain (OS) chickens provides an excellent animal model for the study of Hashimoto's autoimmune thyroiditis in humans. The data presented in this paper indicate that nonspecific esterases (NSE) may play a role in or serve as a marker for the target organ
The development of perirenal fat depots in obese and lean pig fetuses.
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The differentiation of perirenal adipose tissue was ascertained in fetuses from Ossabaw (wild and obese) and cross-bred lean dams at 70, 90 and 110 days gestation and from domestic lean and obese dams (USDA) at 110 days gestation. Condensation of presumptive adipocyte clusters was more apparent in
Cellular and enzyme-histochemical aspects of adipose tissue development in obese (Ossabaw) and lean (crossbred) pig fetuses: an ontogeny study.
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The cellular and enzyme-histochemical differentiation of subcutaneous adipose tissue was studied in lean and obese pig fetuses at several ages. Positive reactions for a variety of cytosolic and organellar enzyme markers indicate metabolic competence of fetal adipocytes despite their small size (12
Gene by sex interaction for measures of obesity in the framingham heart study.
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Obesity is an increasingly prevalent and severe health concern with a substantial heritable component and marked sex differences. We sought to determine if the effect of genetic variants also differed by sex by performing a genome-wide association study modeling the effect of genotype-by-sex
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