ethyl acetate/hypoxia

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Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells.

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Hypoxia-inducible factor-1 (HIF-1) is an important tumor-selective therapeutic target for solid tumors. Icariside II was isolated from Epimedium koreanum through successive fractionation with ethyl acetate, n-butanol, chloroform and hexane, followed by gel column chromatography. Icariside II

Phytochemical analysis of ethyl acetate extract from Astragalus corniculatus Bieb. and brain antihypoxic activity.

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Dry ethyl acetate extract containing flavonoids was obtained from above-ground parts of Astragalus corniculatus Bieb. Seven flavonoids were isolated and identified as rutin, hyperoside, isoquercitrin, narcissin, quercetin, kaempferol and isorhamnetin for the first time. The extract was found to be

Antioxidant potential, total phenolic and total flavonoid contents of Rhododendron anthopogonoides and its protective effect on hypoxia-induced injury in PC12 cells.

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BACKGROUND Rhododendron anthopogonoides Maxim, a kind of traditional Tibetan medicine, has been used to remove body heat, body detoxification, cough, asthma, stomachic and swelling, eliminate abundant phlegm and inflammatory for a long time. In the present study, the total phenols and total

[Effect of hypokinesia and lowered barometric pressure on the tolerance of animals to the action of ethyl acetate].

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Experiments were carried out to study the resistance of rats to an acute effect of ethylacetate vapors at concentrations of 25 to 69 g/m-3 after their 20-day exposure to hypokinesia and 20-day exposure to altitudes of 3200 and 5000 m. The effect of ethylacetate at concentrations of 47 and 10 mg/m-3

An ethyl acetate fraction of Artemisia capillaris (ACE-63) induced apoptosis and anti-angiogenesis via inhibition of PI3K/AKT signaling in hepatocellular carcinoma.

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In cancer treatment, herbal medicines may be a good choice because of the reduced risk of adverse side effects. Artemisia capillaris has been recognized as a promising candidate due to its hepatoprotective effects. Herein, we investigated whether A. capillaris-derived fraction (ACE-63) could inhibit

Dalspinin isolated from Spermacoce hispida (Linn.) protects H9c2 cardiomyocytes from hypoxic injury by modulating oxidative stress and apoptosis.

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Spermacoce hispida (S.hispida), a potential medicinal plant has been traditionally used as an antibacterial, antieczemic, antihypertensive, antidiabetic and antihyperlipidemic agent. Although, this plant has been claimed to protect against oxidative injury and inflammatory conditions

Biodegradation of an inhibitory nongrowth substrate (nitroglycerin) in batch reactors.

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Biodegradation of nitroglycerin (NG), an inhibitory, nongrowth substrate present in a multicomponent munition wastewater, was investigated in a pilot-scale batch reactor operated with both aerobic and anoxic cycles. A mixed culture was initially acclimated by gradual introduction of NG into influent

Carbon Dioxide-induced Bioluminescence Increase in Arachnocampa Larvae

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Arachnocampa larvae utilise bioluminescence to lure small arthropod prey into their web-like silk snares. The luciferin-luciferase light-producing reaction occurs in a specialised light organ composed of Malpighian tubule cells in association with a tracheal mass. The accepted model for

Coffee induces vascular endothelial growth factor (VEGF) expression in human neuroblastama SH-SY5Y cells.

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Recent evidence indicates that hypoxia-inducible vascular endothelial growth factor (VEGF) has neurotrophic and neuroprotective effects on neuronal and glial cells. On the other hand, recent epidemiological studies showed that daily coffee consumption has been associated with a lower risk of several

[Experiment study of blackcurrant on vascular endothelial cells injury induced by hydrogen peroxide].

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OBJECTIVE To study the effect of Blackcurrant on human umbilical vein endothelial ECV-304 cells injury induced by hydrogen peroxide (H2O2). METHODS The H2O2 damaged model was established. The effect of Blackcurrant on injury of ECV-304 activity induced by H2O2 was determined by MTT assay. The levels

Anti-hypoxic activity at simulated high altitude was isolated in petroleum ether extract of Saussurea involucrata.

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BACKGROUND Rhodiola algida, Saussurea involucrata, and other herbs grown in Qinghai-Tibetan plateau have long been used to prevent and treat acute mountain sickness. OBJECTIVE To screen and identify the anti-hypoxic constituents in the herbs grown in Qinghai-Tibetan plateau of Northwestern

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