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Halaman 1 dari 65 hasil
Derivatives of ethylene methanedisulfonate as cancer chemotherapeutic agents
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TECHNICAL FIELD
The present application relates to derivatives of ethylene methanedisulfonate, specifically, derivatives of ethylene methanedisulfonate as cancer chemotherapeutic agents.
BACKGROUND
Alkylating agents are a major class of cancer chemotherapeutic compounds. Many clinically used
Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity
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This invention relates to novel ethylene glycol derivatives which are of value as medicines or antifungal agents.
More particularly, this invention relates to ethylene glycol derivatives, inclusive of salts thereof, which have the formula: ##STR3## wherein n is an integer of 1 to 15; R.sup.1 is an
Method of treating tumors
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TECHNICAL FIELD
The present invention relates to a composition and method for lysing fibrin clots, dissolving thrombi, and reestablishing and maintaining perfusion of ischemic tissue. More particularly, the present invention relates to a composition comprising certain ethylene oxide-propylene oxide
Pharmaceutical compositions for treating certain cancers
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This invention relates to pharmaceutical compounds and to compositions containing them, being primarily concerned with substances of use in the therapy of cancers senstive to those compounds and compositions, of certain non-malignant forms of proliferative disease such as psoriasis, and of certain
Compound, process for its preparation, a pharmaceutical solution containing the compound, a method of determining the presence of cancer, a kit for cancer detection, and the use of hydrolysis of the compound for the detection of cancer
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a U.S. national phase application filed under 35 U.S.C. .sctn. 371 of International Patent Application No. PCT/PL2017/000018 filed Mar. 3, 2017, which in turn claims priority of Polish Patent Application No. P.416395, filed Mar. 4, 2016,
Method for treating a neoplastic disorder
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TECHNICAL FIELD
The present invention generally relates to methods for treating diseases, and more particularly to methods for treating neoplastic disorders using polymers and thermal ablation therapy.
BACKGROUND OF THE INVENTION
Image-guided interventions have become a viable treatment alternative
Sustained release of a therapeutic agent from PLA-PEG-PLA nanoparticles for cancer therapy
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BACKGROUND OF THE INVENTION
Technical Field
The present invention relates to a targeted sustained release PLA-PEG-PLA nanoparticle loaded with a breast cancer therapeutic agent.
Description of the Related Art
The "background" description provided herein is for the purpose of generally presenting the
Method for delivering pharmaceutical nanoparticles to cancer cells
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BACKGROUND OF THE INVENTION
Technical Field
The present invention relates to a targeted sustained release PLA-PEG-PLA nanoparticle loaded with a breast cancer therapeutic agent.
Description of the Related Art
The "background" description provided herein is for the purpose of generally presenting the
Triaryl-ethylene derivatives
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The present invention relates to novel triaryl-ethylene derivatives that are useful as antineoplastic agents, antiatherosclerotic agents, and hypocholesterolemic agents.
The present invention provides novel triaryl-ethylene derivatives of formula: ##STR1## wherein A is a radical of the formula
Triaryl-ethylene derivatives
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The present invention relates to novel triaryl-ethylene derivatives that are useful as antineoplastic agents, antiatherosclerotic agents, and hypocholesterolemic agents.
The present invention provides novel triaryl-ethylene derivatives of formula: ##STR1## wherein
A is a radical of the formula
Prostate cancer treatment
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FIELD OF THE INVENTION
The present invention relates to low molecular weight compounds, useful as antiandrogens, and in particular as antiandrogens with low androgenic activity. The invention further relates to methods for inhibiting androgen receptors and in treating androgen receptor-mediated
Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to a tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent and a preparation method thereof.
2. Description of the Prior Art
The platinum(II) antitumor agent such as cisplatin or
Anti-tumor platinum(II) complexes and process for the preparation thereof
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SUMMARY OF THE INVENTION
The present invention relates to anti-tumor platinum coordination compounds represented by the following general formula I ##STR2## wherein A is selected from the group consisting of ammine and monodentate primary alkyl- and cycloalkylamines having 1-3 carbon atoms such as
Certain tetrahydro-furan or pyran phosphate-ethylene or propylene ammonium derivatives
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BACKGROUND OF THE INVENTION
The present invention relates to a series of novel phosphate ester derivatives containing a cyclic ether system and provides processes for producing these compounds and compositions containing them for use as anti-cancer agents.
Many compounds have been shown to have
pH-sensitive polymeric micelles for drug delivery
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BACKGROUND OF THE INVENTION
This invention relates to drug delivery. More particularly, this invention relates to polymeric micelles for targeted drug delivery, including drug delivery for treating cancer and bypassing multidrug resistance of cancer cells by taking advantage of tumor and endosomal
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