1000mg of (Hesperidin and Diosmin mixture) three times daily for 7 days 1000mg of (Hesperidin and Diosmin mixture) two times daily for 3 days

standard care therapy in quarantine hospitals

Coronavirus Infection

Hesperidin and Diosmin mixture

Hesperidin and Diosmin for Treatment of COVID-19

Randomized Double-blind Controlled Parallel Study of (Hesperidin and Diosmin Mixture) for Treatment of COVID-19 Newly Diagnosed Patients in Egypt

Prof. Dr. Kamal Mohammed Okasha

Professor

Tanta University

Randomized double-blind controlled Parallel study

Daily dietary supplementation with 4 oz. of a commercially available Concord grape juice.

Daily dietary supplementation with 8 oz. of a commercially available Concord grape juice.

Daily dietary supplementation with 16 oz. of a commercially available Concord grape juice.

Daily dietary supplementation with 4 oz. of a placebo beverage

Daily dietary supplementation with 8 oz. of a placebo beverage

Daily dietary supplementation with 16 oz. of a placebo beverage

Gulf War Illness

Daily dietary supplementation with a commercially available Concord grape juice.

Concord grape juice

Daily dietary supplementation with a placebo beverage consisting of water, sugar, artificial flavoring and color that is formulated to look and taste like grape juice and have the same carbohydrate composition and energy load.

Placebo Beverage

Web link for research studies that are open to Gulf War Veteran research at the New Jersey War Related Illness and Injury Study Center

VA- New Jersey Health Care System

Development of a Polyphenol-rich Dietary Preparation for Treating Veterans With Gulf War Illness

to assess safety and tolerability to treatment. The test is a 53-item self report scale that uses the 5 point Likert scale.

to assess safety and tolerability to treatment. The Patient Health Questionnaire 15 (PHQ 15) is a validated measure of somatic symptom severity in functional somatic syndromes (FSS). Scale ranges from 0-30 (mild to severe).

This test looks at cognitive functioning by assessing immediate recall and long-delayed recall.

The Chalder Fatigue Questionnaire assess chronic fatigue. Each of the 11 items are answered on a 4-point scale ranging from the asymptomatic to maximum symptomology

The Digit Span subtest is a widely used measure of auditory attention that is well-normed and sensitive. The subtest has three parts - digits forward, backward, and sequencing.

The CPT-3 assist in clinical assessment of attention problems. The patient is instructed to press the space bar (or mouse button) immediately following the presentation of specific letters on screen. The test normally takes 14 minutes to administer.

The TMT consists of two forms, parts A and B. This measure taps both simple graphomotor speed (Part A) and adds in a rapid set-shifting paradigm that taps executive functioning (Part B).

A tool for testing adult intelligence level.

The Stroop Color and Word Test consists of a Word Page with color words printed in black ink, a Color Page with 'Xs' printed in color, and a color-Word Page with words from the first page printed in colors from the second page (the color and the word do not match). The respondent goes down each sheet reading words or naming the ink colors as quickly as possible within a time limit. The test yields three scores based on the number of items completed on each of the three stimulus sheets. An Interference score, which is useful in determining the individual's cognitive flexibility, creativity, and reaction to cognitive pressures also can be calculated.

This test takes approximately 30 minutes and consists of 120 items, presented visually. The participant must decipher the underlying principle of the stimulus set. Total number of errors will be used.

A tool to measure visuospatial learning and memory abilities.

Digit Span measures short-term auditory memory and attention.

Giulio Maria Pasinetti

Icahn School of Medicine at Mount Sinai

United States Department of Defense

Department of Veterans Affairs, New Jersey

Coltect contains natural compounds: curcumin, green tea and selenium which are approved as food supplements by the Ministry of Health in Israel. Curcumin and green tea are widely used in the food industry.

Ulcerative Colitis

Two tablets twice daily (BID) during the 2 months of the study. Each tablet contains 500mg Curcumin, 250mg Green tea and 100mcg Selenomethionine.

flavonoid/sakit kepala

Hesperidin and Diosmin for Treatment of COVID-19

Development of a Polyphenol-rich Dietary Preparation for Treating Veterans With Gulf War Illness

The Efficacy and Tolerability of Coltect as Add-on in Patients With Active Ulcerative Colitis - an Open Label

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