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folate/atrofi

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Serum folate, homocysteine, brain atrophy, and auto-CM system: The Treviso Dementia (TREDEM) study.

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BACKGROUND The role of folate and homocysteine in brain atrophy associated with Alzheimer's disease is not completely understood. OBJECTIVE The aim of this study was to investigate the relationships between serum folate and homocysteine levels and the degree of cortical-subcortical and hippocampal

Mental deterioration in epilepsy due to folate deficiency.

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Folate deficiency in 50 epileptic children aged 5 to 18 years was treated with a combination of folic acid and vitamin B(12). Improvement in mental condition occurred from five to eight weeks after beginning treatment in some of the younger children; no change was noticed, however, in 31. Similarly,

Serum folate and the severity of atrophy of the neocortex in Alzheimer disease: findings from the Nun study.

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BACKGROUND Previous studies suggested that low concentrations of folate in the blood are related to poor cognitive function, dementia, and Alzheimer disease-related neurodegeneration of the brain. OBJECTIVE Our aim was to determine whether serum folate is inversely associated with the severity of

Subacute combined degeneration of the cord due to folate deficiency: response to methyl folate treatment.

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Subacute combined degeneration of the cord is a rare complication of folate deficiency. Disturbance of methylation reactions in nervous tissue probably underlie subacute combined degeneration of the cord arising from folate as well as vitamin B12 deficiency. Methyl tetrahydrofolate is the form in

[Chorioretinal atrophy in pediatric cerebral folate deficiency-a preventable disease?]

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Cerebral folate deficiency (CFD) results in neurological alterations and a massive degeneration of the choroid/retina if left untreated, which limit the visual field and visual acuity. This article reports the case of a female patient with CFD, who developed autistic personal characteristics prior

Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.

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The case of a 48-year-old woman with a relapsing radial palsy which followed diarrheic episodes is reported. She had low folate concentrations in serum and cerebrospinal fluid, as well as low and borderline values of cerebrospinal fluid and erythrocyte folates. She had chronic gastrointestinal

Case report: subacute combined degeneration of the spinal cord from folate deficiency.

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Subacute combined degeneration of the spinal cord is a rare neurologic complication of folate deficiency. Progressive gait disturbance, weakness, confusion, and depression developed in a 39-year-old man. He had taken phenobarbital for more than 2 years. He was bedbound, with new loss of position and

High Serum Folate Is Associated with Brain Atrophy in Older Diabetic People with Vitamin B12 Deficiency.

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Previous studies have reported the adverse cognitive effects of high folate status in older individuals with vitamin B12 (VB12) deficiency. Thus, the aim of this study was to investigate how high serum folate and VB12 deficiency could collaboratively aggravate neuronal degeneration. In total, 146

Functional and psychic deterioration in elderly people may be aggravated by folate deficiency.

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The deterioration of functional and mental capacity is one of the major problems of the elderly. This deterioration may be caused or worsened by folate deficiency. The aim of this investigation was to analyze the relationship between mental and functional capacities and folate status in a group of

Folate status worsens in recently institutionalized elderly people without evidence of functional deterioration.

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OBJECTIVE To follow folate status, hematological and cognitive changes during the first year of institutionalization among elderly subjects. METHODS Prospective study. METHODS Long-stay unit of the Dijon University Geriatric Hospital. METHODS Twenty women and four men older than 65 years admitted

Subacute combined degeneration of the spinal cord due to folate deficiency in association with a psychotic illness.

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Subacute combined degeneration of the cord which occurred as a result of dietary deficiency of folic acid in a patient with a psychotic illness, is described. A significant improvement in the neurological deficit occurred following treatment with folic acid. It is possible that treatment with folate

Subacute combined degeneration of the cord, dementia and parkinsonism due to an inborn error of folate metabolism.

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A 2-year-old girl with 5,10-methylenetetrahydrofolate reductase deficiency developed subacute combined degeneration of the cord and a leuco-encephalopathy which was confirmed at necropsy. Total folate concentrations in serum, red cells and CSF were markedly reduced whereas vitamin B12 concentrations
OBJECTIVE To assess associations between increased serum homocysteine, low vitamin B12, low folate, and age-related macular degeneration (AMD). METHODS Population-based, cross-sectional analysis. METHODS Serum homocysteine, vitamin B12, and folate were measured in 2,335 participants of the Blue

Homocysteine, folate, vitamin B-12, and 10-y incidence of age-related macular degeneration.

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BACKGROUND Epidemiologic evidence of a relation between serum total homocysteine (tHcy), vitamin B-12, and folate and age-related macular degeneration (AMD) is inconsistent and unresolved. OBJECTIVE In this cohort study, we aimed to investigate associations between intakes and serum concentrations
BACKGROUND There is growing evidence of the importance of nutrition in age-related macular degeneration (AMD), but few studies have explored associations with folate and B vitamins. No effective therapeutic strategy for geographic atrophy (GA) is available, and prevention could be of great
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