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Role of Co-trimoxazole in Severe COVID-19 Patients

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Coronavirus disease (COVID-19) caused by SARS-COV2, represents a highly transmissible and potentially fatal disease that is of great global public health concern at this moment. The pandemic situation in Bangladesh is also evolving rapidly with positive cases and deaths increasing each day.

s100β, NSE n GFAP in Living Donor Hepatectomy and Delirium

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The postoperative delirium picture is a serious and common complication seen after any major surgery, including hepatic resection. Delirium is an acute state of confusion characterized by impaired consciousness, reduced ability to focus on attention, changes in cognitive functions, a perceptual

Chilean Gastric Cancer Task Force (FORCE 1)

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Participating entities: The Chilean Gastric Cancer Task Force (GCTF) is a collective effort between two principal identities: 1- The Center of Excellence of Precision Medicine (CEMP), which was established through a joint funding by the government agency for economic development (Corporacion de

Prevention of Malaria in HIV-uninfected Pregnant Women and Infants

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Pregnant women will be scheduled to be seen in the clinic every 4 weeks during their pregnancy and then 1 and 6 weeks following delivery. In addition, pregnant women will be instructed to come to the study clinic for all their medical care and avoid the use of any outside medications. Children will

Bendamustine and Rituximab Combination Therapy for Cold Agglutinin Disease

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Background Chronic cold agglutinin disease (CAD) is mediated by monoclonal cold-reactive autoantibodies that bind to erythrocyte surface antigens, causing hemagglutination and complement-mediated hemolysis. Anemia is severe in one-third of patients (hemoglobin level 8.0 g/dL or lower). Cold-induced

Chemoradiation for Bone Metastasis

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BACKGROUND Much of the clinical practice of oncology involves palliative care. In this setting ,the emphasis is on alleviation of symptoms and preservation or improvement of quality of life. A large body of clinical evidence documents the effectiveness of local-field external beam radiotherapy in

Pemetrexed Plus Oxaliplatin as Adjuvant Chemotherapy for Radically Resected Non-Small Cell Lung Cancer

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Non-small cell lung cancer (NSCLC) accounts for the largest number of cancer deaths annually, worldwide. (Ferlay et al, 2007) Of these, about 30% are early stage patients (stage I and II). For this group of patients, radical surgery with mediastinal lymph node dissection has been the mainstay of

Vitamin A and Maternal-infant Flu Vaccine Response

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Influenza morbidity affects the entire population and has an enormous impact upon the economic burden and the health care system, particularly causing serious illness among young infants 0-6 months of age. Recent studies show high rates of influenza illness and hospitalization among infants at this

Voraxaze for Delayed Methotrexate Clearance

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Researchers want to learn how glucarpidase may impact patients' length of stay in the hospital, kidney function, and quality of life. Also, researchers want to learn if glucarpidase may decrease the incidence of neutropenic fever, which may decrease the use of antibiotics by vein to treat this kind

Therapy for Chronic Cold Agglutinin Disease

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1. Background Chronic cold agglutinin disease (CAD) is mediated by monoclonal cold-reactive autoantibodies that bind to erythrocyte surface antigens, causing haemagglutination and complement-mediated haemolysis. Anaemia is severe (Hb 8.0 g/dL or lower) in one-third of patients and complement-induced

Control of Pregnancy Associated Malaria With Intermittent Preventive Treatment

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General Objective To evaluate an alternative strategy of community involvement in the control of pregnancy associated malaria and anaemia in an area of intense malaria transmission in Ghana. Specific Objectives To explore local knowledge and health-care practices of control of malaria in pregnancy

Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

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There are multiple secondary objectives in this trial: - To estimate the overall event-free survival of patients treated with risk-directed therapy - To identify the plasma methotrexate (MTX) concentrations that produce maximum intracellular accumulation of active metabolites (methotrexate

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