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Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
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BACKGROUND AND SUMMARY
Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging
Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
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BACKGROUND AND SUMMARY
Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging
Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
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Masuk daftar
BACKGROUND AND SUMMARY
Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging
Folate targeted enhanced tumor and folate receptor positive tissue optical imaging technology
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BACKGROUND AND SUMMARY
Cancer survival statistics establish the importance of early detection and thorough tumor resection for maximization of patient lifespan. Recent efforts to better achieve these objectives have focused on development of safer, more sensitive, and more discriminating imaging
IgA Fc-folate conjugates, pharmaceutical compositions and methods to treat cancer
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FIELD OF THE DISCLOSURE
The present disclosure provides IgA antibody fragment crystallizable region (Fc)-Folate conjugates that selectively target and kill cancer cells expressing folate receptors. The Fc-Folate conjugates are particularly useful to treat breast cancer, including triple negative
N.sub.3S.sub.1 chelator-folate derivatives, preparation method thereof and composition for diagnosis or treatment of cancer containing the same as an active ingredient
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority from Korean Patent Application No. 10-2012-0119743, filed on Oct. 26, 2012, and Korean Patent Application No. 10-2013-0127479, filed Oct. 25, 2013, in the Korean Intellectual Property Office, the contents of each of which are
Induction of tumor immunity by variants of folate binding protein
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FIELD OF THE INVENTION
The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by
Induction of tumor immunity by variants of folate binding protein
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FIELD OF THE INVENTION
The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by
Induction of tumor immunity by variants of folate binding protein
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Masuk daftar
FIELD OF THE INVENTION
The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by
Induction of tumor immunity by variants of folate binding protein
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FIELD OF THE INVENTION
The present invention is directed to the fields of cancer and immunology. Specifically, the present invention is directed to compositions and methods for tumor vaccines directed to tumor antigens and is directed to specific epitopes on these antigens that are recognized by
Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
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FIELD OF THE INVENTION
This invention relates to novel difluoroglutamic acid conjugates with folates and anti-folates, to the use of these conjugates in the treatment of neoplastic diseases, and to intermediates used in the preparation of the conjugates.
BACKGROUND OF THE INVENTION
Folates and
Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
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FIELD OF THE INVENTION
This invention relates to novel difluoroglutamic acid conjugates with folates and anti-folates, to the use of these conjugates in the treatment of neoplastic diseases, and to intermediates used in the preparation of the conjugates.
BACKGROUND OF THE INVENTION
Folates and
Combination therapy for cancer using HSP27 inhibitor and EGFR tyrosine kinase inhibitors or anti-folates
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FIELD OF THE INVENTION
This application relates to combination therapy for the treatment of cancer using inhibitors of heat shock protein 27 (Hasp 27) and an epidermal growth factor tyrosine kinase inhibitor (EGFR-TKI) such as erlotinib, or antifolates such as pemetrexed.
BACKGROUND OF THE
Methods of treating cancer in a patient by administering anti-folate-receptor-1 (FOLR1) antibodies
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REFERENCE TO A SEQUENCE LISTING SUBMITTED ELECTRONICALLY VIA EFS-WEB
The Sequence Listing submitted Mar. 29, 2017, as a text file named "2921.0440004_SequenceListing_ST25," created on Mar. 28, 2017, and having a size of 68,562 bytes, is hereby incorporated by reference pursuant to 37 C.F.R. .sctn.
Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use
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BACKGROUND
Thapsigargin (TG) is a naturally-occurring compound that is highly specific for inhibiting the sarco/endoplasmic reticulum and endoplasmic reticulum Ca.sup.2+-ATPase pump (SERCA). The inventors recently identified TG as a modulator of Notch (Roti G., et al., "Complementary genomic screens
Database tanaman obat terlengkap yang didukung oleh sains
- Bekerja dalam 55 bahasa
- Pengobatan herbal didukung oleh sains
- Pengenalan herbal melalui gambar
- Peta GPS interaktif - beri tag herba di lokasi (segera hadir)
- Baca publikasi ilmiah yang terkait dengan pencarian Anda
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Ketikkan gejala atau penyakit dan baca tentang jamu yang mungkin membantu, ketik jamu dan lihat penyakit dan gejala yang digunakan untuk melawannya.
* Semua informasi didasarkan pada penelitian ilmiah yang dipublikasikan
