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Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis).
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The structure of a new prenylated coumarin (E-omega-benzoyloxyferulenol, 1b) from the Sardinian giant fennel (Ferula communis) has been confirmed by synthesis. The parent compound ferulenol (1a) showed sub-micromolar antimycobacterial activity, which was partly retained in 1b and in the simplified
Bactericidal action of a glycoprotein from the body surface mucus of giant African snail.
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1. Bactericidal action of a glycoprotein, Achacin, purified from the giant African snail, Achatina fulica Férussac, has been studied. 2. Achacin kills both gram-positive and gram-negative bacteria, but only in their growing states. 3. Achacin does not have any bacteriolytic activity. 4. The strain
Molecular cloning of the antibacterial protein of the giant African snail, Achatina fulica Férussac.
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An expression cDNA library was constructed with poly(A)-rich RNA extracted from the collar of the giant African snail, Achatina fulica Férussac. A 1.9-kbp cDNA clone encoding a precursor of antibacterial glycoprotein of the snail, achacin, was isolated from the cDNA expression library. The cDNA
Expression of giant silkmoth cecropin B genes in tobacco.
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Cecropin B is a small antibacterial peptide from the giant silkmoth Hyalophora cecropia. To reveal the potential of this peptide for engineering bacterial disease resistance into crops, several cecropin B gene constructs were made either for expression in the cytosol or for secretion. All constructs
Personalised antimicrobial dosing: standing on the shoulders of giants
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The suboptimal use of antimicrobial drugs contributes to the increasing antimicrobial resistance and may lead to therapy failure at the individual patient level. Considering the significant pharmacokinetic (PK) variation in special patient populations and the variability in pathogen susceptibility,
Analysis of Antibacterial Activity and Bioactive Compounds of the Giant Mushroom, Macrocybe gigantea (Agaricomycetes), from India.
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The antibacterial activity, phenolic profile, and bioactive compounds of fruiting bodies from 2 strains (MA1 and MA2) of the giant mushroom Macrocybe gigantea were evaluated to access their nutraceutical efficacy. The antibacterial activity was higher in MA2 against all selected pathogenic bacteria.
Cellulose-dependent expression and antibacterial characteristics of surfactin from Bacillus subtilis HH2 isolated from the giant panda.
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Surfactin secreted by Bacillus subtilis can confer strong, diverse antipathogenic effects, thereby benefitting the host. Carbon source is an important factor for surfactin production. However, the mechanism that bacteria utilize cellulose, the most abundant substance in the intestines of herbivores,
Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.
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Immunity to mycobacteria involves the formation of granulomas, characterized by a unique macrophage (MΦ) species, so-called multinucleated giant cells (MGC). It remains unresolved whether MGC are beneficial to the host, that is, by prevention of bacterial spread, or whether they promote
Interaction of Giant Unilamellar Vesicles with the Surface Nanostructures on Dragonfly Wings.
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The waxy epicuticle of dragonfly wings contains a unique nanostructured pattern that exhibits bactericidal properties. In light of emerging concerns of antibiotic resistance, these mechano-bactericidal surfaces represent a particularly novel solution by which bacterial colonization and the formation
Identification and function of 11 Rab GTPases in giant freshwater prawn Macrobrachium rosenbergii.
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Rab GTPases, members of the Ras-like GTPase superfamily, are central elements in endocytic membrane trafficking. However, little is known of the Rab genes in the giant freshwater prawn Macrobrachium rosenbergii. In this study, 11 Rab genes were identified from M. rosenbergii. All MrRabs have a RAB
Clearfil Protect Bond™ versus Uni-Etch™ antibacterial self-etchant: A war of giants against shear bond strength.
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OBJECTIVE
To use antibacterial agents with two conventional bonding systems and evaluate the shear bond strength (SBS) of bracket to enamel.
METHODS
Overall, 120 human-extracted first premolars were used. The specimens were equally divided into six sub-groups of 20 samples. Control groups were
Magainin-H2 effects on the permeabilization and mechanical properties of giant unilamellar vesicles.
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Among the potential novel therapeutics to treat bacterial infections, antimicrobial peptides (AMPs) are a very promising substitute due to their broad-spectrum activity and rapid bactericidal action. AMPs strongly interact with the bacterial membrane, and the need to have a correct understanding of
Investigation of antibacterial activity of Bacillus spp. isolated from the feces of Giant Panda and characterization of their antimicrobial gene distributions.
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Bacillus group is a prevalent community of Giant Panda's intestinal flora, and plays a significant role in the field of biological control of pathogens. To understand the diversity of Bacillus group from the Giant Panda intestine and their functions in maintaining the balance of the intestinal
Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander (Andrias davidianus).
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Peptidoglycan (PGN) recognition proteins (PGRPs) are important pattern recognition receptors (PRRs) involved in immune defense against bacterial infections. In this study, a short PGRP (termed AdPGRP-S1) was cloned and functionally characterized from Chinese giant salamander (Andrias davidianus),
Giant Phospholipid Folds on Air-Water Surface: Structure Details, Formation Pathway, and Possible Recycle Mechanism.
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In vitro mimics recognized that the propensity of a negatively charged phospholipid, DPPS, monolayers to self-aggregate to three-dimensional (3D) giant folds under overcompression at an air-water interface. Time elapsing microscopical observations confirmed that such giant folds were able to float
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