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giant/phosphatase
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TESTICULAR ACID PHOSPHATASE IN GIANT SILKMOTHS.
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Giant intrathyroidal parathyroid adenoma.
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Primary hyperparathyroidism (PHPT) is not an uncommon endocrine disorder. However, acute primary hyperparathyroidism, or parathyroid crisis (PC), is a rare clinical entity characterized by life-threatening hypercalcemia of a sudden onset in patients with PHPT. We describe a patient with PC who
[Central giant cell granuloma. Histochemical and ultrastructural study on giant cell function (author's transl)].
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Multinucleated giant cells in giant cell granuloma are formed by cell fusion of capillary pericytes. In our present study we tried to analyze cell function and activity by histologic, histochemical, and electronmicroscopic examination of giant cells. Lysosomal enzymes such as acid phosphatase and
Giant cells in arthritic synovium.
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OBJECTIVE
Giant cells are commonly present in inflamed synovium, often in close association with the intimal layer. The nature of these multinucleate cells has been reassessed using new cytochemical and immunochemical techniques.
METHODS
Cryostat sections of non-inflamed, rheumatoid arthritic and
Clinical and histologic features of 26 canine peripheral giant cell granulomas (formerly giant cell epulis).
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Clinical and histologic features of 26 cases of canine peripheral giant cell granuloma (formerly giant cell epulis) are reported. Two main histologic categories were evident: (1) "classic" peripheral giant cell granuloma, characterized by variable numbers of multinucleated giant cells (MNGCs)
[Purification and study of the characteristics of the multinucleated giant cells of the giant cell tumor].
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OBJECTIVE
To harvest high purified osteoclast-like giant cells from the giant cell tumor by using trypsin and EDTA(ethylenediamineteraacetic acid) digestion. And explore the role and the origin of the multinucleated giant cells of the giant cell tumor.
METHODS
Multinucleated giant cells were
Giant-cell arteritis and raised serum-alkaline-phosphatase levels.
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Presentation of occult giant cell arteritis.
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Temporal headache, blindness, and polymyalgia rheumatica are well-recognized manifestions of giant cell arteritis. However, the disease may present in less evident fashion as shown by 30 of 74 patients with biopsy-proven giant cell arteritis whose predominant complaint was not one ot these cardinal
[A case of giant prostate cancer].
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A 67-year-old patient with stage C giant prostate cancer was treated with a combination of endocrine administration and chemotherapy. After administration of diethylstilbestrol diphosphate (250 mg/D, 16 days), bilateral orchiectomy and subsequent CDDP administration (30 mg/D X 5 days, e. 3 weeks, 4
Multinucleate foreign-body giant cell formation.
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The formation of multinucleate giant cells (MGCs) was studied after the subcutaneous implantation of cellophane foil into 25 Wistar rats. Epitheloid cells fuse to form MGCs of the Langhans type, with nuclei at the cell periphery that later migrate to the central cell region (Touton's type). Both
Gene expression in giant-cell tumors.
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Malignant transformation is thought to be associated with changes in the expression of a number of genes, and this alteration in gene expression is considered critical to the development of the malignant phenotype. In this study, gene expression in 8 samples of giant-cell tumor (GCT) of bone, as
[A case of giant prostatic cystadenoma].
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An 80-year-old man was admitted to our hospital with the chief complaint of urinary retention. On physical examination, a large tumor was recognized in pelvic cavity. Serum levels of prostatic acid phosphatase and gamma-seminoprotein were elevated. Anterior pelvic exenteration was performed because
Similarities between giant cell tumor of bone, giant cell tumor of tendon sheath, and pigmented villonodular synovitis concerning ultrastructural cytochemical features of multinucleated giant cells and mononuclear stromal cells.
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The authors investigated ultrastructural cytochemical features of multinucleated and mononuclear stromal cells in giant cell tumor of bone (GCTB), giant cell tumor of tendon sheath (GCTTS), and pigmented villonodular synovitis (PVNS). Specimens of each tumor, respectively numbering 4, 4, and 3, were
Osteoclast origin of giant cells in giant cell tumors of bone: ultrastructural and cytochemical study of six cases.
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To clarify the histogenesis of giant cells appearing in giant cell tumors of bone (GCTB), an ultrastructural and cytochemical study of six cases was performed with both acid phosphatase (ACPase) and tartrate-resistant acid phosphatase (TRACPase) as marker enzymes. TRACPase is considered a specific
Giant cell tumor of bone. Fine structural localization of alkaline phosphatase.
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The fine structural localization of nonspecific alkaline phosphatase was elucidated in two giant cell tumors of bone using lead as capturing ion and beta-glycerophosphate as substrate in the incubation solution. Lead phosphate precipitate--indicating presence of alkaline phosphatase--was
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