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glioma/sembap

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The use of magnetic resonance imaging (MRI) is the current standard for the delineation of target volumes for high-grade gliomas (HGG). While the peritumoral edema as per T2-weighted (T2W) imaging is utilized as basis to delineate the initial borders of the clinical target volume (CTV), those areas
Objective. To evaluate the efficacy of Wulingsan subtraction ( WLSS) decoction in the treatment of postoperative brain edema and fever as a complication of glioma neurosurgery. Methods. This retrospective study was conducted at the Department of Neurosurgery of Liaocheng People's Hospital. Patients
Peritumoral edema is a key stage in the infiltration and recurrence of glioma. Photodynamic therapy (PDT) increases the extent of peritumoral edema, which leads to a decrease in the effectiveness of PDT in treating glioma. The present study evaluated the effects of PDT combined with torasemide on

The role of extracellular-5'-nucleotidase/CD73 in glioma peritumoural brain edema.

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During pathological conditions, extracellular-5'-nucleotidase/CD73 can protect neurons by reducing the permeability of the blood brain barrier. In recent years, it has been demonstrated that CD73 can negatively contribute to the growth of gliomas; however, the function of CD73 in glioma blood

Peritumoral edema on magnetic resonance imaging predicts a poor clinical outcome in malignant glioma.

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Peritumoral edema (PTE), one of the main characteristics of malignant glioma, is a significant contributor to the morbidity and mortality from glioma, however, a recent systematic review suggested that controversy remains with regard to its prognostic value. To further determine whether PTE was a

Cell swelling following recovery from acidification in C6 glioma cells: an in vitro model of postischemic brain edema.

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Two consequences of cerebral ischemia are cell acidification and cytotoxic edema. To test the possibility that Na+/H+ exchange mediates acid-induced edema, we measured cytoplasmic pH (pHi) and cell volume changes in C6 glioma cells that were artificially acid-loaded using weak electrolytes. pHi was

Glioma prostaglandin levels correlate with brain edema.

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The present study was designed to prospectively investigated the prostaglandin (PG) levels and extent of peritumoral edema in 30 cases of glioma by using methods of radioimmunoassay and imaging. Both TXB2 and 6-keto-PGF1 alpha levels in all glioma groups went up over that in the control group. TXB2

Neurotransmitter amines in brain edema of a rat glioma model.

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The effect of vasogenic brain edema on amine neurotransmitter concentrations was studied in rats bearing transplanted glioma C6 brain tumors. In comparison with sham-operated and nonoperated controls, the tumor-implanted animals showed significant decreases in both dopamine (DA) and norepinephrine
To identify a novel treatment modality for postoperative, glioma-related refractory cerebral edema (RCE), eight patients with postoperative RCE received chemotherapy between January 2008 and July 2012 were enrolled. There were five males and three females aged between 24 and 65 years (mean 45.7

Effects of metformin treatment on glioma-induced brain edema.

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Considerable evidence has demonstrated that metformin can activate 5'-AMP-activated protein kinase (AMPK) signaling pathway, which plays a critical role in protection of endothelial cell permeability. Hence, the present study evaluated the effects of metformin on blood brain barrier permeability and
BACKGROUND Carmustine (BCNU) wafer (Gliadel(®) Wafer) implantation after tumor resection is an approved treatment for high-grade glioma (HGG). These wafers change various characteristics on early postoperative magnetic resonance imaging (ep-MRI) including slight expansion of high-intensity areas on

[To the mechanism of edema around malignant brain glioma].

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Based on the results of a comparative study (magnetic resonance imaging and/or computed tomography with a morphological study) in 11 patients with malignant brain glioma, the authors have ascertained that the extent of perifocal edema cannot fully reflect the degree of impairment of the blood-brain

[Effect of brain edema on the recurrence pattern of malignant gliomas].

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OBJECTIVE To assess the influence of initial preoperative brain edema in malignant gliomas on regrowth patterns. METHODS 79 patients with histologically verified supratentorial malignant glioma were prospectively studied by magnetic resonance imaging (MRI) before and every 2-3 months after surgery.

[Correlation of influencing factors with the extent of peritumoral brain glioma edema].

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OBJECTIVE To explore the correlation of various influencing factors with the extent of peritumoral brain glioma edema. METHODS A total of 69 glioma cases were confirmed by pathology after operation. And stepwise multiple linear regression analysis was performed on gender, age, Karnofsky performance

Differentiation of edema and glioma infiltration: proposal of a DTI-based probability map.

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Conflicting results on differentiating edema and glioma by diffusion tensor imaging (DTI) are possibly attributable to dissimilar spatial distribution of the lesions. Combining DTI-parameters and enhanced registration might improve prediction. Regions of edema surrounding 22 metastases were compared
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