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The Effect of a SGLT2 Inhibitor on Glucose Flux, Lipolysis and Exercise in Type 2 Diabetes

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SGLT2 inhibitors are a new class of drug that have a novel mechanism of action by promoting urinary glucose excretion to lower blood glucose levels. The recent observations that ketogenesis or episodes of diabetic ketoacidosis seem to be of higher frequency in patients with Type 1 and Type 2

Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle Mass

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Design. This is a prospective case-control study investigating fat and glucose metabolism in patients with low muscle mass during prolonged fasting, comparing results to those found in healthy controls. Setting. All children were admitted to the Department of Pediatrics and Adolescents medicine,

Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract

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Malnutrition is characterized by a negative energy balance due to a deep skeletal muscular loss, which is itself secondary to the reduction of intake and metabolic abnormalities aggravating the loss of weight. Sarcopenia is defined as the loss of muscle mass, the consequences of which are a decrease

Bedside Monitoring of Cerebral Energy State During the Peri-cardiac Arrest Period

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Microdialysis assessment of cerebral energy state during cardiac arrest and cardiopulmonary resuscitation in humans In comatose patients resuscitated from out of hospital cardiac arrest (OHCA), neurological injuries remain the leading cause of death. The in-hospital mortality is reported at 30-50%,

The Effects of Bariatric Surgeries on Non-Alcoholic Fatty Liver Disease

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35 consecutive patients referred for bariatric surgery will be recruited either at the obesity clinic, or from inpatient (scheduled for bariatric surgery). A detailed history and a complete physical examination will be done at the first visit along with anthropometric measures; routine blood tests,

A Longitudinal Study on Short-term Effects of Gastric Bypass on Glucose Homeostasis in Obesity

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In 1987 Pories et al. (1) published that after gastric bypass 99% of morbidly obese patients became and remained euglycaemic over time. However, the most interesting observation of these authors (1) was that the patients were converted to euglycaemia within 10 days of the operation, even if before

Age-Related Changes in Proliferation and Differentiation Capacity of Human Preadipocytes From Periorbital Fat.

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Understanding the age-related changes in periorbital adipose tissue is crucial for improving current rejuvenation techniques, or developing new ones. However, no such study has been reported in the literature. Hundreds of people came to our hospital requesting upper blepharoplasty every year. Taking

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