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Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to anti-cancer drug and, more particularly, to synthetic dicinnamate compounds and their analogues that exhibit anti-tumor activity and/or an anti-inflammatory activity, that has beneficial activity principally in
Cryoprotected, frozen recombinant cancer cells
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FIELD OF THE INVENTION
The invention relates to compositions and methods for the cryopreservation of cellular vaccines. More specifically, the invention relates to the use of particular compositions comprising cryoprotective media that includes hydroxyethyl starch (HES) and glycerol or DMSO together
Oligosialyl-1,2-dialkyl-sn-glycerols and synthetic intermediates for their preparation
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TECHNICAL FIELD
The present invention relates to oligosialyl-1,2-dialkyl-sn-glycerols and synthetic intermediates for their preparation. More specifically, it relates to .alpha.2 .fwdarw.8 oligosialyl-1,2-dialkyl-sn-glycerols and synthetic intermediates for their preparation, and processes for
Phosphonates as anti-cancer agents
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FIELD OF THE INVENTION
This invention pertains to the synthesis and use as anti-cancer therapeutic agents of a group of substances with a glycerol backbone linked to phosphonocholine or other phosphorus-containing head groups.
BACKGROUND OF THE INVENTION
European Patent No. P0230 575A2, dated Apr.
Use of monomycolyl glycerol (MMG) as an adjuvant
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a national stage of International Patent Application No. PCT/DK2008/000239, filed Jun. 26, 2008.
FIELD OF INVENTION
The present invention discloses the use of monomycolyl glycerol (MMG), a synthetic homologue, analogue or modified version
Retinoid glycerol phospholipid conjugates
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Priority is claimed to provisional patent application Ser. No. 60/009,546, filed Jan. 2, 1996.
TECHNICAL FIELD
The present invention relates to certain alkyl and alkenyl glycerophosphoethanolamines substituted with a retinoid ester moiety on the glyceryl backbone, and to pharmaceutical compositions
Modified ether glyceroglycolipids
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FIELD OF THE INVENTION
This invention is directed to modified ether glyceroglycolipids, compositions containing these compounds, and to the therapeutic administration of these compounds and compositions to animals, including those afflicted with cancers, as well as various other diseases and
Modified ether glyceroglycolipids
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1. Filed of the Invention
This invention is directed to modified ether glyceroglycolipids, compositions containing these compounds, and to the therapeutic administration of these compounds and compositions to animals, including those afflicted with cancers, as well as various other diseases and
(2'-nitro-1'-imidazolyl)-2,3-isopropylidene-y-tosylbutanol, a precursor to [.sup.18 F]fluoroerythronitroimidazole PET imaging agent
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BACKGROUND OF THE INVENTION
Field of the Invention
Tumor cells are more sensitive to radiation in the presence of oxygen than in its absence Powers et al., 1963). Even a small percentage of hypoxic cells within a tumor could limit response to radiation (Hall, 1988). Hypoxic radioresistance has been
Contrast resolution tissue mimicking phantoms for nuclear magnetic resonance imaging with stable NMR properties
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FIELD OF THE INVENTION
This invention pertains generally to products and techniques for testing the resolution capabilities of nuclear magnetic resonance (NMR) imaging equipment and particularly to imaging processes in which hydrogen is the monitored nucleus.
BACKGROUND OF THE INVENTION
The early
Plasmalogen compounds, pharmaceutical compositions containing the same and methods for treating diseases of the aging
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FIELD OF INVENTION
The present invention relates to the synthesis and utility of novel chemical entities with useful biochemical, physiochemical, and clinical properties. More specifically, a series of 1-alkyl, 2-acyl glycerol derivatives are provided which can be used for the treatment or
Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in the treatment of various disorders
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BACKGROUND OF THE INVENTION
The present invention relates to compounds, pharmaceutical compositions, and methods for treating several conditions with prodrugs for phenylacetate as therapeutic agents.
FIELD OF THE INVENTION
Phenylalkanoic acids are known therapeutic agents for a variety of disorders.
Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in the treatment of various disorders
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BACKGROUND OF THE INVENTION
The present invention relates to compounds, pharmaceutical compositions, and methods for treating several conditions with prodrugs for phenylacetate as therapeutic agents.
1. Field of the Invention
Phenylalkanoic acids are known therapeutic agents for a variety of
Rapid synthesis and use of 18F-fluoromisonidazole and analogs
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BACKGROUND OF THE INVENTION
Field of the Invention
Tumor cells are more sensitive to radiation in the presence of oxygen than in its absence Powers et al., 1963). Even a small percentage of hypoxic cells within a tumor could limit response to radiation (Hall, 1988). Hypoxic radioresistance has been
Structured triglycerides and emulsions comprising same
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FIELD OF INVENTION
The present invention relates to structured triglycerides, to emulsions comprising same suitable for parenteral nutrition, and use thereof. In particular, the invention relates to structured triglycerides comprising at least one medium chain C.sub.6-C.sub.12 fatty acid and at
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