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Juvenile gout in Taiwan associated with family history and overweight.
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OBJECTIVE
To examine the clinical features of juvenile gout and its possible association with familial juvenile hyperuricemic nephropathy (FJHN).
METHODS
A total of 543 cases of juvenile gout from the Ho-Ping Gout Database were enrolled, and 5269 gouty cases with onset age of 40 to 50 years were
Obesity Paradox in Recurrent Attacks of Gout in Observational Studies: Clarification and Remedy.
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Obesity is strongly associated with incident gout risk, but its association with the risk of recurrent gout attacks has been null or weak, constituting an obesity paradox. We sought to demonstrate and overcome the methodologic issues associated with the obesity paradox for risk of recurrent gout
Obesity, Echocardiographic Changes and Framingham Risk Score in the Spectrum of Gout: A Cross-Sectional Study.
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[Endothelial dysfunction as a marker of vascular aging syndrome on the background of hypertension, coronary heart disease, gout and obesity].
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Under observation were 40 hypertensive patients with coronary heart disease, gout and obesity I and II degree. Patients with hypertension in combination with coronary heart disease, gout and obesity, syndrome of early vascular aging is shown by increased stiffness of arteries, increased peak
The effect of diet-induced obesity on the inflammatory phenotype of non-adipose-resident macrophages in an in vivo model of gout.
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OBJECTIVE
Gout is strongly associated with obesity. The aim of this study was to determine if obesity altered the inflammatory phenotype of non-adipose tissue-resident macrophages in response to the gout-causing agent monosodium urate (MSU) crystals.
METHODS
C57BL/6J mice were fed a high-fat diet
Hyperlipoproteinaemia in primary gout: hyperlipoproteinaemic phenotype and influence of alcohol intake and obesity in Japan.
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Serum lipoprotein profiles were investigated in 108 male patients with primary gout before treatment to elucidate the prevalence of each individual phenotype of coexisting hyperlipoproteinaemia and pathogenic factors responsible for it. The mean serum triglyceride (TG) and total cholesterol (TC)
Gout and hyperlipidaemia. Effect of overweight on the levels of circulating lipids.
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A study of the serum lipids in 90 patients with gout and 90 controls matched for age and weight index demonstrated that in gout there was a significant elevation of the mean serum levels of cholesterol (282 +/- 55 mg/100 ml), triglycerides (183 +/- 161 mg/100 ml) and phospholipids (270 +/- 61 mg/100
Visceral fat obesity is highly associated with primary gout in a metabolically obese but normal weighted population: a case control study.
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BACKGROUND
Gout is a chronic inflammatory disease the development of which is associated with obesity-induced metabolic abnormalities. However, a substantial number of non-obese patients (body mass index [BMI] <25 kg/m(2)) also develop gout in Korea. It was suggested that accumulation of visceral
Obesity and younger age at gout onset in a community-based cohort.
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OBJECTIVE
Obesity is associated with gout risk. It is unclear whether obesity is associated with a younger age at gout onset. We examined whether obesity is related to age at gout onset and quantified the risk of incident gout by obesity status in the Campaign Against Cancer and Heart Disease (CLUE
Impact of obesity and hypertriglyceridemia on gout development with or without hyperuricemia: a prospective study.
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OBJECTIVE
Hyperuricemia is the most important risk factor for the development of gout; however, not all patients with hyperuricemia develop gout, and patients experiencing a gout attack are not necessarily found to have hyperuricemia. We hypothesized that the interactions between serum uric acid
A case-control study of the association of diet and obesity with gout in Taiwan.
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BACKGROUND
Gout has been a significant metabolic disorder for Chinese men in Taiwan; however, there is insufficient information on diet and lifestyle risk factors in this population.
OBJECTIVE
The purpose of this case-control study was to explore potential dietary and lifestyle risk factors
Management of hyperuricemia and gout in obese patients undergoing bariatric surgery.
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BACKGROUND
Hyperuricemia and gout represent important issues in the obese patients. Considering the epidemic trend of overweight and obesity in developed countries, the impact of these conditions is likely to increase. At present, bariatric surgery represents the most effective treatment for the
Effects of bariatric surgery on gout incidence in the Swedish Obese Subjects study: a non-randomised, prospective, controlled intervention trial.
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OBJECTIVE
To assess the long-term effect of bariatric surgery on the incidence of gout and hyperuricaemia in participants of the Swedish Obese Subjects (SOS) study.
METHODS
This report includes 1982 subjects who underwent bariatric surgery and 1999 obese controls from the SOS study, a prospective
Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.
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BACKGROUND
Gout treatment remains suboptimal. Identifying populations at risk of developing gout may provide opportunities for prevention. Our aim was to assess the risk of incident gout associated with obesity, hypertension and diuretic use.
METHODS
We conducted a systematic review and
Incident gout in women and association with obesity in the Atherosclerosis Risk in Communities (ARIC) Study.
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BACKGROUND
We hypothesized that women with early- and mid-adult life obesity, as well as high mid-adult life waist-to-hip ratios, and high weight gain during adulthood, experience a greater incidence of gout.
METHODS
We examined the incidence of gout in the Atherosclerosis Risk in Communities Study,
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