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hemorrhage/obesitas
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Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Organic compounds
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The present invention relates to novel imidazole derivatives that are used as aldosterone synthase and aromatase inhibitors, as well as for treatment of a disorder or disease mediated by aldosterone synthase or aromatase.
The present invention provides a compound of formula (I)
##STR00002## wherein
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein
R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl,
R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Protein kinase inhibitors
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FIELD OF THE INVENTION
The present invention relates to isoquinoline derivatives, to pharmaceutical compositions containing the isoquinoline derivatives, their use as inhibitors of protein kinase, as well as to processes for the preparation and use of such molecules.
BACKGROUND OF THE
Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or peptidomimetics
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FIELD OF THE INVENTION
The present invention relates to ATP mimetics, particularly isoquinoline derivatives, conjugated to a peptide or peptidomimetic, pharmaceutical compositions containing the isoquinoline derivatives and conjugates, their use as inhibitors of protein kinase, as well as to
Aryl sulfonamides and sulfamide derivatives and uses thereof
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Throughout this application, various references are referred to within parentheses. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains. Full bibliographic
Aryl sulfonamides and sulfamide derivatives and uses thereof
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Throughout this application, various references are referred to within parentheses. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains. Full bibliographic
Aryl sulfonamides and sulfamide derivatives and uses thereof
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Throughout this application, various references are referred to within parentheses. Disclosures of these publications in their entireties are hereby incorporated by reference into this application to more fully describe the state of the art to which this invention pertains. Full bibliographic
Oligomeric ketone compounds
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The present invention relates to novel oligomeric compounds which have utility as Nutraceutical and/or medicaments for producing ketosis in humans and animals for nutraceutical or therapeutic purposes.
It is known that ketone bodies, particularly (R)-3-hydroxybutyrate (D-.beta.-hydrotybutyrate) and
1,4-dithiin and 1,4-dithiepin-1,1,4,4, tetroxide derivatives useful as antagonists of the human galanin receptor
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FIELD OF THE INVENTION
This invention relates to a series of 1,4-dithiin- and 1,4-dithiepin-1,1,4,4-tetroxide derivatives and their use for the treatment of central nervous system disorders and affective conditions. More particularly, the compounds of the invention are ligands for the human galanin
Sulphonamide derivatives, their preparation and their therapeutic application
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FIELD OF THE INVENTION
The present invention relates to sulfonamide derivatives, to the process for preparing them and to their therapeutic use.
BACKGROUND OF THE INVENTION
Orexins A and B (or hypocretins 1 and 2) are hypothalamus neuropeptides of 33 and 28 amino acids, respectively, recently
Aminoalkyl substituted 5,6,7,8-Tetrahydro-9H-Pyridino [2,3-B]indole derivatives
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to aminoalkyl substituted 5,6,7,8-tetrahydro-9H-pyridino[2,3-b]indole and 5,6,7,8-tetrahydro-9H-pyrimidino[4,5-b]indole derivatives, pharmaceutical compositions containing such compounds and their use in treating
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