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huntington disease/hypoxia

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PCP receptor ligands and the use thereof

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FIELD OF THE INVENTION The invention is in the field of pharmaceutical compositions which are useful for the prevention and/or treatment of neurodegradation and other neuropathological conditions in animals. BACKGROUND OF THE INVENTION The amino acid L-glutamate is widely thought to act as a

PCP receptor ligands and the use thereof

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FIELD OF THE INVENTION The invention is in the field of pharmaceutical compositions which are useful for the prevention and/or treatment of neurodegradation and other neuropathological conditions in animals. BACKGROUND OF THE INVENTION The amino acid L-glutamate is widely thought to act as a

Crystalline forms of tricyclic compound acid salt or hydrate thereof, and method for making thereof

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TECHNICAL FIELD The present disclosure relates to novel crystalline acid salts of a tricyclic derivative or a hydrate thereof, and a production method thereof. BACKGROUND Drugs administered orally show medicinal effects through absorption, distribution, metabolism or elimination, and the intrinsic

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention is in the field of medicinal chemistry. In particular, this invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical composition comprising the same, which possess neuroprotective capability. This invention further relates

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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BACKGROUND OF THE INVENTION This invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods for treating any disease of the nervous system in

N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention is in the field of medicinal chemistry. In particular, this invention relates to N,N'-disubstituted guanidine analogues, and to compounds and pharmaceutical composition comprising the same, which possess neuroprotective capability. This invention further relates

Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Tri-and tetra-substituted guanidines and their use as excitatory amino acid antagonists

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FIELD OF THE INVENTION This invention relates to tri- and tetra-substituted guanidines, and to pharmaceutical compositions comprising the same, which possess neuroprotective capability. This invention further relates to methods involving the use of these compounds as excitatory amino acid

Amino acid derivatives of substituted quinoxaline 2,3-dione derivatives as glutamate receptor antagonists

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BACKGROUND OF THE INVENTION This invention is for novel glutamate receptor antagonists which are new compounds of the 5,6,7,8-substituted quinoxaline 2,3-dione type. The fused ring system is substituted at the a- or b-position by amino acid derivatives. The compounds are active as excitatory amino

Alkyl amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists

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BACKGROUND OF THE INVENTION This invention is for novel glutamate receptor antagonists which are new compounds of the 5,6,7,8-substituted quinoxaline 2,3-diones type. The fused ring system is substituted at the a- or b-position by amino acid derivatives. The compounds are active as excitatory amino
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