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hyperandrogenism/sembap
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Use of flutamide for self-induced androgen excess. A case report.
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A 28-year-old woman developed hirsutism, facial edema and clitoromegaly after self-injection of long-acting synthetic androgens. The symptoms were ameliorated by administration of flutamide with a combination oral contraceptive. Flutamide appears to be useful in preventing sequelae of acute androgen
Massive ovarian edema with androgen secretion. A pathological and endocrine study with review of the literature.
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A case of massive edema of the left ovary with virilization is described. Microscopically, massive interstitial edema with luteinization of theca and stromal cells was found. A few stromal cells contained Reinke-type crystalloids--an original observation. Peripheral concentrations of testosterone,
Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report.
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BACKGROUND
Mature, benign cystic teratomas of the ovary are common in reproductive-age women, but they are very rarely associated with androgen production and subsequent development of hirsutism or virilization. We describe a case of postmenopausal hirsutism and hyperandrogenism caused by a mature
Fibromatosis and massive edema of the ovary, possibly related entities: a report of 14 cases of fibromatosis and 11 cases of massive edema.
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Twenty-five cases of ovarian enlargement secondary to massive edema, to a hitherto undescribed lesion that we have designated fibromatosis, or to both processes were reviewed to explore the possibility of a relation between them. The patients ranged in age from 13 to 39 years. The 14 patients with
Bilateral mucinous cystadenomas and massive edema of the ovaries in a virilized adolescent girl.
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BACKGROUND
Ovarian pathology, including nonfunctional tumors and massive edema of the ovary, has been associated with stromal luteinization and clinical endocrinopathies.
METHODS
An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation
Prenatal diagnosis for congenital adrenal hyperplasia in 532 pregnancies.
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Congenital adrenal hyperplasia (CAH) refers to a family of monogenic inherited disorders of adrenal steroidogenesis most often caused by enzyme 21-hydroxylase deficiency (21-OHD). In the classic forms of CAH (simple virilizing and salt wasting), androgen excess causes external genital ambiguity in
The Complex Interaction Between Polycystic Ovary Syndrome and Hereditary Angioedema: Case Reports and Review of the Literature.
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UNASSIGNED
Hereditary angioedema (HAE) is a rare but severe disease, with high risk of death, and attacks have been associated to high estrogen levels. Polycystic ovary syndrome (PCOS) is a common hyperandrogenic condition, which is frequently treated with combined oral
PREOPERATIVE TREATMENT WITH METYRAPONE IN PATIENTS WITH CUSHING'S SYNDROME DUE TO ADRENAL ADENOMA.
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OBJECTIVE
Metyrapone has been approved for the treatment of patients with Cushing's syndrome (CS), but only few retrospective clinical studies are available. The aim of our study was the prospective assessment of metyrapone as pre-operative treatment.
METHODS
Before adrenalectomy, 7 patients with
The essential role of IGF-I: lessons from the long-term study and treatment of children and adults with Laron syndrome.
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Fifty patients with primary GH resistance (Laron syndrome) due to molecular defects of the GH receptor or post-receptor pathways were followed from infancy through adulthood. This condition leading to long-term insulin-like growth factor-I (IGF-I) deprivation caused marked growth retardation (-4 to
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