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hyperlipidemias/phosphatase
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Protein tyrosine phosphatase inhibitors and methods of use thereof
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FIELD OF THE INVENTION
This invention relates to the field of protein tyrosine phosphatase inhibition.
BACKGROUND OF THE INVENTION
This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B.
Reversible protein tyrosine phosphorylation, coordinated by the
Protein tyrosine phosphatase inhibitors and methods of use thereof
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FIELD OF THE INVENTION
This invention relates to the field of protein tyrosine phosphatase inhibition.
BACKGROUND OF THE INVENTION
This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B.
Reversible protein tyrosine phosphorylation, coordinated by the
1,2,5-thiazolidine derivatives useful for treating conditions mediated by protein tyrosine phosphatases (PTPase)
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This application is the National Stage of Application No. PCT/EP2006/046543, filed on Dec. 6, 2006, which claims benefit under 35 U.S.C. .sctn.119(a-d) of U.S. Provisional Application No. 60/748,491, filed Dec. 8, 2005, the contents of which are incorporated herein by reference in their
Oxindole hydrazide modulators of protein tyrosine phosphatases (PTPs)
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FIELD OF THE INVENTION
The present invention is related to the use of oxindole hydrazide derivatives of formula (I) for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin
Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs)
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FIELD OF THE INVENTION
The present invention is related to substituted methylene amide derivatives of formula (I), in particular for the treatment and/or prevention of metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose
Methods and compositions for acid phosphatase-1 gene inhibition
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FIELD OF THE INVENTION
This invention relates generally to the field of human genetics. More specifically, the invention relates to diagnosis of susceptibility to hyperlipidemia, especially hyperlipidemia associated with metabolic syndrome. The invention further relates to methods for screening drug
Aromatic farnesyl compound and application thereof
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REFERENCE TO CORRESPONDING APPLICATIONS
The present application is the 371 national stage application based on International Application No. PCT/CN2015/097938, filed Dec. 18, 2015, which claims priority to Chinese Patent Application No. 20151057895.1, filed Sep. 11, 2015, Chinese Patent Application
Azole compound and medicinal use thereof
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TECHNICAL FIELD
The present invention relates to a novel azole compound, more particularly, the present invention relates to an azole compound or a pharmaceutically acceptable salt thereof having a protein tyrosine phosphatase 1B (PTP1B) inhibitory activity, and a pharmaceutical composition
1-orthofluorophenyl substituted 1,2,5-thiazolidinedione derivatives as PTP-as inhibitors
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The present invention relates to thiadiazolidinone derivatives, pharmaceutical compositions containing such compounds, methods of making such and methods of treating conditions mediated by protein tyrosine phosphatases by employing such compounds.
Accordingly, the present invention provides
Organic compounds
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The present invention relates to thiadiazolidinone derivatives, pharmaceutical compositions containing such compounds, methods of making such and methods of treating conditions mediated by protein tyrosine phosphatases by employing such compounds.
Accordingly, the present invention provides
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