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iatrogenic disease/hypoxia

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Pathophysiology of radiocontrast nephropathy: a role for medullary hypoxia.

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Recent experimental data underlies the role of hypoxic tubular injury in the pathophysiology of radiocontrast nephropathy. Although systemic transient hypoxemia, increased blood viscosity, and a leftward shift of the oxygen-hemoglobin dissociation curve may all contribute to intrarenal hypoxia,
Background: Approximately 14% of UK hospital in-patients receive supplemental oxygen therapy, but only 57% have valid prescriptions. Oxygen must be optimally prescribed to ensure maximal therapeutic response whilst minimising adverse

Mandible Osteoradionecrosis

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Osteoradionecrosis (ORN) of the mandible is a severe iatrogenic disease of devitalized bone caused by radiation therapy of oral and oropharyngeal cancers. It is a state of injured bone tissue with inadequate healing or remodeling response of at least three to six months. The wound can result from

[Contrast-induced nephropathy].

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Contrast-induced nephropathy (CIN) is an iatrogenic disorder, resulting from procedures requiring the intravascular administration of iodinated contrast media. It has an association with increased morbidity and mortality, increased costs and it remains the third most common cause of

A reexamination of the role of oxygen in retrolental fibroplasia.

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A critical review of the literature of retrolental fibroplasia indicates that the cause of this disease is not yet known. Oxygen is certainly a critical factor but it is still not possible to make precise recommendations as to the amount or the duration of therapy that is safe. We have
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