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iatrogenic disease/serotonin
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Iatrogenesis and the recent selective serotonin reuptake inhibitor debate.
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Serotonin syndrome and other serotonergic disorders.
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Serotonin syndrome is an iatrogenic disorder induced by pharmacologic treatment with serotonergic agents that increases serotonin activity. In addition, there is a wide variety of clinical disorders associated with serotonin excess. The frequent concurrent use of serotonergic and neuroleptic drugs
Iatrogenesis and neurological manifestations in the elderly.
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Older people are often exposed to polypharmacy in a multimorbidity context. Inappropriate polypharmacy is often harmful, increasing the risk of inappropriate prescriptions and therefore adverse drug events (ADEs). Five to 20% of all hospital admissions are related to ADE in older people, among which
A perfect storm in the emergency department.
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BACKGROUND
Serotonin syndrome is an iatrogenic disorder that results from serotonergic overactivity. Severe myoclonus and increased restlessness are hallmarks of the disorder.
METHODS
We report a case of serotonin syndrome related to poor drug elimination.
RESULTS
A 74-year-old white female with
[Prescription drug in the elderly. Study of changes in treatment during a stay in 221 geriatric patients in the Lyon region].
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Prescribe in the elderly has specifcities, with age-related pharmacologica modifications, polypharmacy, and risk of drug toxicity. At time of the prescription renewal, each drug must be re-evaluated. The objective of this study was to identify the nature and reasons of drugs modifications during a
Involvement of cytochromes p450 in drug-drug interactions: an overview.
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Drug interactions can cause iatrogenic disease. If concurrent medications are taken, the potential exists for a drug interaction to occur. Renewed interest in the topic interactions has been generated by the fatal interactions involving non-sedating histamine H-1 antagonists and the recent
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