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l rhamnose/radang
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Plasma citrulline concentration: a reliable marker of small bowel absorptive capacity independent of intestinal inflammation.
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OBJECTIVE
Postabsorptive plasma citrulline concentration has been proposed as a reliable marker of small bowel absorptive capacity in short bowel patients. The aim of this study was to address the potentially confounding impact of intestinal inflammation.
METHODS
Fifty-five patients were selected
Intestinal permeability and inflammation in patients on NSAIDs.
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BACKGROUND
The frequency with which non-steroidal anti-inflammatory drugs (NSAIDs) increase small intestinal permeability and cause inflammation is uncertain.
OBJECTIVE
To examine small intestinal permeability and inflammation in a large number of patients on long term NSAIDs.
METHODS
Sixty eight
The sugar permeability test reflects disease activity in children and adolescents with inflammatory bowel disease.
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OBJECTIVE
To investigate the relationship of intestinal permeability in children and adolescents with inflammatory bowel disease (IBD) to disease activity, disease extent, and response to therapy.
METHODS
Patients with new and established diagnoses of IBD (12 Crohn's disease [CD] and 18 ulcerative
Importance of local versus systemic effects of non-steroidal anti-inflammatory drugs in increasing small intestinal permeability in man.
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Increased small intestinal permeability caused by non-steroidal anti-inflammatory drugs (NSAIDs) is probably a prerequisite for NSAID enteropathy, a source of morbidity in patients with rheumatoid arthritis. This increased small intestinal permeability may be a summation of a local effect during
Isolation of polysaccharides from Dendrobium officinale leaves and anti-inflammatory activity in LPS-stimulated THP-1 cells.
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Dendrobium officinale stem is rich in polysaccharides, which play a great role in the medicinal effects of this plant. However, little was known about the polysaccharides from Dendrobium officinale leaves. Two kinds of polysaccharides in the leaves, DLP-1 and DLP-2, were obtained by hot water
Metronidazole reduces intestinal inflammation and blood loss in non-steroidal anti-inflammatory drug induced enteropathy.
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This study assessed the effect of metronidazole on the gastroduodenal mucosa, intestinal permeability, blood loss, and inflammation in patients on non-steroidal anti-inflammatory drugs (NSAIDs). Thirteen patients were studied before and after 2-12 weeks' treatment with metronidazole 800 mg/day,
Effects of therapy with lansoprazole on intestinal permeability and inflammation in young cystic fibrosis patients.
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BACKGROUND
Defective pancreatic bicarbonate secretion with low intestinal pH or intestinal inflammation of any origin increase intestinal permeability in cystic fibrosis (CF).
METHODS
In this open study, the authors evaluated the effect of a proton-pump inhibitor on intestinal permeability and
Studies on lectins of amago (Oncorhyncus rhodurus). I. Amago ova lectin and its receptor on homologous macrophages.
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A lectin was found in the ova of amago, a Japanese trout (Oncorhyncus rhodurus), which agglutinates rabbit, rat and human B-type erythrocytes. The hemagglutination was specifically inhibited by monosaccharides, L-rhamnose, D-galactose, and their C2 and C4 analogs, and
The effect of bariatric surgery on intestinal absorption and transit time.
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BACKGROUND
Bariatric surgical procedures are classified by their presumed mechanisms of action: restrictive, malabsorptive or a combination of both. However, this dogma is questionable and remains unproven. We investigated post-operative changes in nutrient absorption and transit time following
N-acetyl-D-galactosamine inhibits TNF-alpha gene expression induced in mouse peritoneal macrophages by fimbriae of Porphyromonas (Bacteroides) gingivalis, an oral anaerobe.
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Adherence to host cells is an essential step in the initiation of most infectious diseases. It is well known that bacterial fimbriae may be involved in the adherence. Porphyromonas (Bacteroides) gingivalis is a pathogenic organism of adult periodontitis which is a chronic inflammatory disease. Using
The effect of polyacrylic acid polymers on small-intestinal function and permeability changes caused by indomethacin.
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Non-steroidal anti-inflammatory drug (NSAID)-induced increased small-intestinal permeability appears to be a prerequisite for the development of NSAID enteropathy, which is a cause of much morbidity in patients with rheumatoid arthritis. We assessed, with a combined absorption-permeability test, the
COX-2 inhibition with rofecoxib does not increase intestinal permeability in healthy subjects: a double blind crossover study comparing rofecoxib with placebo and indomethacin.
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BACKGROUND
Acute and chronic use of non-steroidal anti-inflammatory drugs can increase intestinal permeability. Rofecoxib, which selectively inhibits cyclooxygenase 2 (COX-2), is a novel anti-inflammatory drug with the potential to produce minimal gastrointestinal toxic effects while retaining
Glucose and citrate reduce the permeability changes caused by indomethacin in humans.
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Nonsteroidal anti-inflammatory drug (NSAID)-induced increased intestinal permeability appears to be a prerequisite for NSAID enteropathy. It has been suggested that early metabolic events leading to the permeability changes may involve inhibition of glycolysis and the tricarboxylic acid cycle, in
Differential trafficking of saccharidic probes following aspirin in clinical tests of intestinal permeability in young healthy women.
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The effects of inflammatory changes on the absorption of different-sized probes and their permeability ratios are poorly understood. The aim of the present study was to determine the effects of a pharmacological agent on the permeability of the gut mucosa to saccharidic probes of larger and smaller
The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.
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BACKGROUND
The treatment of septic conditions in critically ill patients is still one of medicine's major challenges. Cyclic nucleotides, adenosine and its receptors play a pivotal role in the regulation of inflammatory responses and in limiting inflammatory tissue destruction. The aim of this study
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