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Mucin and fat emboli in mucinous carcinomas. Cause of hemorrhagic cerebral infarcts.
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A patient with a mucin-producing carcinoma of the breast died after three weeks of progressive neurologic deterioration. At autopsy, numerous small hemorrhagic cerebral infarcts of varying ages were found. The infarcts were primarily located in arterial boundary zones of cerebral and cerebellar
Hemorrhagic infarcts caused by mucin emboli mimicking brain purpura.
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The macroscopic aspect of brain purpura was mimicked by multiple hemorrhagic infarcts arising in the vascular supply region of small arteries occluded by embolized mucin in a case of scar adenocarcinoma of the right lower pulmonary lobe, which had extensively permeated pulmonary blood vessels. The
Lung metastases manifesting as pulmonary infarction by mucin and tumor embolization: radiographic, high-resolution CT, and pathologic findings.
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We present a case of lung metastasis manifesting as lung infarction by mucin and tumor embolization. The radiograph and high-resolution CT showed multiple focal consolidations with ground glass attenuation in subpleural areas of both lungs. Diagnosis was made by open lung biopsy, which revealed
Acute cerebral infarction during combination chemotherapy with s-1 and cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach.
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We report a 29-year-old woman with gastric cancer who developed Trousseau's syndrome, a malignancy-related thromboembolism, during chemotherapy. She was diagnosed with a mucin-producing adenocarcinoma of the stomach, and chemotherapy with S-1 and cisplatin was commenced. During treatment, she
Cerebral infarction associated with benign mucin-producing adenomyosis: report of two cases.
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BACKGROUND
Cerebral infarction associated with a malignant tumor is widely recognized as Trousseau syndrome. In contrast, few cases of cerebral infarction associated with benign tumors have been reported. We present two cases of embolic stroke that seemed to be caused by mucin-producing
Mucin-producing adenocarcinomas and nonbacterial thrombotic endocarditis: pathogenetic role of tumor mucin.
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The clinicopathologic data of 5 patients who died of nonbacterial thrombotic endocarditis (NBTE) and disseminated thrombosis and multiple infarcts associated with mucin-producing adenocarcinomas were presented. Histochemical studies on the valvular vegetations and thrombi revealed that
Intravascular mucinosis with mucin emboli and thrombosis accompanying adenocarcinomas.
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Three cases of adenocarcinoma that were complicated by nonbacterial thrombotic endocarditis and disseminated intravascular coagulation are described. In two of these cases mucin was demonstrable within vascular channels as well as within the thrombotic vegetations of the cardiac valves. This
Circulating mucopolysaccharide (mucin) in two adults with metastatic adenocarcinoma. Detection in peripheral blood smear and at autopsy.
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We report two cases of circulating mucin that occurred in women with metastatic adenocarcinoma. In both women, mucin was seen on the peripheral blood smear, but no difficulties were encountered in counting blood cells. In one patient, the mucin was grossly visible in the plasma and within
Cerebral infarction developing in a patient without cancer with a markedly elevated level of mucinous tumor marker.
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Previous studies have shown the possible role of mucin in cerebral infarction associated with coagulation abnormalities in patients with cancer, particularly adenocarcinoma. We report a 42-year-old woman who developed motor aphasia and cerebral infarction in the left frontal lobe and right parietal
Mucin embolism to cerebral arteries: a fatal complication of carcinoma of the breast.
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The case is reported of a woman with a mucin producing lobular carcinoma of the breast with metastases to many bone sites, whose terminal neurological illness was the result, not of cerebral metastases, but of cerebral infarcts. These were caused by emboli of mucin and emulsified fat, originating in
[Acute myocardial infarction and bronchoalveolar carcinoma. Association or coincidence?].
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The aim of this paper is to report for the first time the association between bronchiolo-alveolar carcinoma and acute myocardial infarction (AMI). Two patients suffering from this association were studied. A 59 year old male, diabetic, alcoholic and smoker was admitted because a diaphragmatic AMI.
Nonbacterial Thrombotic Endocarditis Complicated by Cerebral Infarction in a Patient with Adenomyosis with High Serum CA125 Level; A Case Report.
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We report a case of a 48-year-old woman with multiple cerebral infarctions caused by nonbacterial thrombotic endocarditis (NBTE) because of adenomyosis with high serum carbohydrate antigen (CA)125 level. Transesophageal echocardiography (TEE) showed a vegetation, 4 mm in diameter, adjacent to the
Inhibition of T cell immunoglobulin and mucin-1 (TIM-1) protects against cerebral ischemia-reperfusion injury.
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High titers of CA-125 may be associated with recurrent ischemic strokes in patients with cancer.
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In addition to etiologies common in the general population, strokes in cancer patients may be caused by hypercoagulable states, hyperviscosity, cardiogenic embolism, and neoplastic vessel infiltration. Intravascular mucins were reported in patients with recurrent thromboembolism. The authors report
Sclerosing mucoepidermoid carcinoma of the parotid gland.
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Although mucoepidermoid carcinoma is the most common primary malignancy of the salivary glands, the sclerosing morphologic variant of this tumor is extremely rare, with only 6 reported cases. As its name suggests, sclerosing mucoepidermoid carcinoma is characterized by an intense central sclerosis
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