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multiple myeloma/albumin
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Serum albumin level is a significant prognostic factor reflecting disease severity in symptomatic multiple myeloma.
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Serum albumin level, in association with serum interleukin-6 level, is a significant prognostic factor in multiple myeloma patients. The aim of this study was to determine any clinical factors associated with decreased serum albumin level. We retrospectively reviewed the records of 373 patients
Prognostic Significance of Initial Serum Albumin and 24 Hour Daily Protein Excretion before Treatment in Multiple Myeloma.
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Renal failure is a common morbidity in multiple myeloma (MM). Although proteinuria has been increasingly reported in malignancies, it is not routinely used to refine risk estimates of survival outcomes in patients with MM. Here we aimed to investigate initial serum albumin and 24-hour daily protein
The albumin and monoclonal protein ratio as prognostic marker for multiple myeloma in the era of novel agents.
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Multiple myeloma (MM) is a heterogeneous disease group regarding prognosis, clinical course, and response to therapeutic interventions. Numerous prognostic factors have been identified however there was no consensus about the best prognostic indicators or the proper staging systems. In a previous
Comparison of bromcresol green and agarose protein electrophoresis for quantitation of serum albumin in multiple myeloma.
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BACKGROUND
The International Staging System for multiple myeloma has increased the importance of accurate measurement of serum albumin. Two common albumin assays, bromcresol green (BCG) and agarose gel protein electrophoresis (PEL), frequently yield discordant results, creating confusion regarding
Multiple myeloma staging based on the combination of beta-2-microglobulin and albumin: the role of albumin in the model.
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OBJECTIVE
Since the prognostic significance of the combination of beta-2-microglobulin (beta(2)m) and albumin in multiple myeloma (MM) has been recognized, these two easily obtainable parameters were subsequently employed in the staging systems of Bataille et al. (BSS), the South West Oncology Group
Stratification of multiple myeloma according to serum beta 2-microglobulin and serum albumin levels.
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In 71 patients with multiple myeloma the authors evaluated the clinical significance and the prognostic relevance of Bataille's stratification system based on serum beta 2-microglobulin and serum albumin levels. This staging system, which classified the patients to low, intermediate and poor risk
Globulin fraction and albumin: globulin ratio as a predictor of mortality in a South African multiple myeloma cohort
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Multiple myeloma, a hematological malignancy typified by the clonal expansion of bone marrow plasma cells, contributes to one percent of all malignancies worldwide. Despite myeloma only contributing to 10% of all hematological malignancies, it carries significant morbidity owing to its heterogenous
Hemodiafiltration with ultrafiltrate regeneration reduces free light chains without albumin loss in multiple myeloma patients
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Background: Acute kidney injury (AKI) occurs in 12-20% of multiple myeloma (MM) patients. Several studies have shown a reduction of free light chains (FLC) using hemodialysis with High-Cut-Off membranes. However, this technique entails
Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
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The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway mediates multiple myeloma (MM) cell proliferation, survival, and development of drug resistance, underscoring the role of mTOR inhibitors, such as rapamycin, with potential anti-MM activity. However, recent data
Natural antibodies against tubulin, actin myoglobin, thyroglobulin, fetuin, albumin and transferrin are present in normal human sera, and monoclonal immunoglobulins from multiple myeloma and Waldenström's macroglobulinemia may express similar antibody specificities.
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Sera from a pool of 800 healthy donors and from 3 individual healthy donors were passed through tubulin, actin, thyroglobulin, myoglobin, fetuin, transferrin and albumin immunoadsorbents. Proteins were eluted in all the immunosorbents and were found to be essentially composed of the three major Ig
Comparison of bromcresol purple and capillary protein electrophoresis for quantification of serum albumin in multiple myeloma.
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Treatment of multiple myeloma with radioactive iodine and radioactive iodinated serum albumin.
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Influence of protein and albumin levels on serum fructosamine concentration in a diabetic patient with multiple myeloma.
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The persistence in the blood of the radioactive label of albumins, gamma globulins, and globulins of intermediate mobility. VII. Uptake and die-away plots of S35 into serum albumins and gamma globulins after oral administration of labeled methionine in idiopathic hypogammaglobulinemia and multiple myeloma.
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[Properties and composition of serum albumin in multiple myeloma].
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