Dexamethasone 0.6 mg/kg IV (max 15 mg) before departure from the ED.

The control group received a similar looking placebo (NaCl 0,9% IV) with the same volume.

Migraine

The intervention of interest was the administration of dexamethasone 0.6 mg/kg IV (max 15 mg) before departure from the ED. The control group received a similar looking placebo (NaCl 0,9% IV) with the same volume.

Dexamethasone group

Placebo group

CHU Sainte Justine

RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED

Randomised Controlled Trial of Intravenous Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Pediatric Emergency Department

by questionnaire (heartburns, constipation, personality changes such as irritability, and sleeping problem ad 7 days

Geneviève Tourigny-Ruel

Paediatric Emergency Physician

St. Justine's Hospital

First Episode Psychosis

Minocycline + treatment as usual. 50 mg twice daily increasing to 200 mgs per day, increments of 50 mgs every 2 weeks.

Minocycline

Placebo

Department of Neurology, Psychiatry and Psychological Medicine, University of San Paulo

Civil Hospital Karachi

Karwan e Hayat

Institute of Psychiatry, Rawalpindi medical College

Role of Minocycline in First Episode Psychosis

A Randomised, Double Blind Pilot Study of Minocycline and Placebo Added to Treatment-as-Usual (TAU) in First-Episode Psychosis

Dr Imran B Chaudhry

Stanley Medical Research Institute

Rawalpindi Medical College, Pakistan

Pakistan Institute of Living and Learning

University of Sao Paulo

Labor, Premature

Arm A:
Nifedipine 20 mg sublingual, repeated after 30 minutes if contractions do not decrease in intensity. Maintenance of 120-160 mgs of slow-release nifedipine daily for 48 hours.Once contractions cease, nifedipine will be maintained at 80-120 mg daily in divided doses up to 36 weeks.
Arm B:
Nifedipine 10 mg sublingual crushed, then 10 mg in 15 min, followed by 10 mg PO Q 15 mins PRN to a maximum of 40 mg in the first hour. Maintenance of 60-80 mgs of slow-release nifedipine daily for 48 hours. Once contractions cease, nifedipine will be maintained at 60 mg daily in divided doses up to 36 weeks.

myasthenia gravis/mual

RCT of IV Dexamethasone to Prevent Relapse in the Treatment of Migraine in a Paediatric ED

Role of Minocycline in First Episode Psychosis

Two Dose Regimens of Nifedipine for the Management of Preterm Labor

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