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naphthalene/kanker
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Method for treating or preventing breast cancer or leukemia using 6-[3-[1-adamantyl]-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN)
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FIELD OF THE INVENTION
The present invention relates to the use of a retinoid having unique properties for the treatment or prevention of breast cancer or leukemia. More specifically, the present invention relates to the use of 6-[3-[1adamantyl]-4-hydroxyphenyl]-2-naphthalene carboxylic acid (AHPN)
Composition and method for treating cancer
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FIELD OF THE INVENTION
This invention relates to a composition and a method useful in treating a number of different types of cancers, and, in particular, carcinomas or melanomas. More particularly, this invention relates to a pharmaceutical composition containing a select class of rhodacyanine dyes
Naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists
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BACKGROUND OF THE INVENTION
This invention relates to compounds and methods for treating prostaglandin E mediated diseases, and certain pharmaceutical compositions thereof. More particularly, the compounds of the invention are structurally different from NSAIDs and opiates, and are antagonists of
Naphthalene-based two-photon fluorescent probes, preparation method and use thereof
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FIELD OF THE INVENTION
The present invention relates to a novel category of naphthalene-based two-photon fluorescent probes, their synthesizing methods and a method of utilizing the naphthalene-based two-photon fluorescent probes to label the tumor cells or tissues.
BACKGROUND OF THE
Methods for treating resistant tumors
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BACKGROUND OF THE INVENTION
Along with surgery and radiotherapy, chemotherapy continues to be an effective therapy for many cancers. In fact, several types of cancer are now considered to be curable by chemotherapy and include Hodgkin's disease, large cell lymphoma, acute lymphocytic leukemia,
Process for producing optically active naphthalene derivative and optical resolver therefor
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TECHNICAL FIELD
The present invention relates to a production method of an optically active naphthalene derivative having a pharmacological action, particularly a steroid C.sub.17,20 -lyase inhibitory activity, a reagent for optical resolution thereof and a production method of the reagent for
Naphthalene diimide compounds
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the U.S. national stage application of International Patent Application No. PCT/GB2008/051131, filed Nov. 28, 2008, which claims priority to Great Britain Application No. 0723439.6, filed Nov. 29, 2007, the disclosures of each of which are
Treatment of premalignant lesions and certain malignant tumors
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BACKGROUND OF INVENTION
This invention is directed to the treatment of premalignant lesions and malignant tumors. It has been known to utilize the compound 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-(alpha-methylstyryl)naphthalene which has the formula ##STR1## for the systemic and topical treatment
Naphthalene derivatives, their production and use
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This application is a 371 of PCT/JP99/02143, filed on Apr. 22, 1999.
TECHNICAL FIELD
The present invention relates to a medicine, especially to novel naphthalene derivatives having steroid C.sub.17,20 -lyase inhibitory activity, or its production and pharmaceutical compositions containing the
Naphthalene derivatives, their production and use
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TECHNICAL FIELD
The present invention relates to a medicine, especially to novel naphthalene derivatives having steroid C.sub.17,20-lyase inhibitory activity, or its production and pharmaceutical compositions containing the same.
BACKGROUND ART
It is known that, in the biosynthesis of androgen in
Naphthalene-based inhibitors of anti-apoptotic proteins
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BACKGROUND
1. Field of the Invention
The present invention relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune
Naphthalene-based inhibitors of anti-apoptotic proteins
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FIELD OF THE DISCLOSURE
The disclosure relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune diseases, and/or
Naphthalene-based inhibitors of anti-apoptotic proteins
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FIELD OF THE DISCLOSURE
The disclosure relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune diseases, and/or
1-(4-(Substituted alkoxy)benzyl)naphthalene compounds having estrogen inhibitory activity
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TECHNICAL FIELD
The present invention relates to organic compounds having pharmacological activity, to compositions containing the compounds, and to a medical method of treatment.
More particularly, the present invention concerns a class of 1-[4-(substituted alkoxy)benzyl]naphthalene compounds
Naphthalene derivatives
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The invention relates to compounds of formula I ##STR2## wherein the dotted line indicates the presence or absence of an additional bond, Az is heteroaryl bonded by way of a ring nitrogen atom, Z is a substituent other than hydrogen, and each of R.sub.1 and R.sub.2 independently of the other is
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