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naphthalene/radang
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Naphthalene derivatives having anti-inflammatory activity
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The present invention relates to pharmaceutically active naphthalene derivatives, to processes for their preparation and to pharmaceutical compositions containing them.
Certain naphthalene derivatives are known to possess useful anti-flammatory activity and to be suitable for use in the treatment of
Trichosporon sp RRLY-15 (DSM 11829) and its use to prepare S(+)-6-methoxy-methyl-2-naphthalene acetic acid
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FIELD OF INVENTION
This invention relates to the filed of biotechnology. It describes an efficient bio-resolution process for the preparation of an anti-inflammatory drug S(+)-6-methoxy-.alpha.-methyl-2-naphthalene acetic acid (naproxen) of formula (2). Through the bio-resolution process, two
Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic
Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF THE INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR)
Aryl substituted naphthalene derivatives
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BACKGROUND OF THE INVENTION
The present invention relates to certain aryl substituted naphthalene, benzoxepine, benzazepine and benzocycloheptene derivatives.
SUMMARY OF THE INVENTION
The present invention relates to a compound having the structural formula I: ##STR1## or a pharmaceutically
Method of treating inflammatory, tissue repair and infectious conditions
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Growth factors comprise a family of polypeptides with a manyfold of properties regulating for example cell proliferation and cell metabolism. As being multi-functional molecules, they may stimulate or inhibit cell proliferation as well as affect cell function depending on the type of the target
Treatment of chronic inflammatory joint disease with arylsulfonamides
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BACKGROUND OF THE INVENTION
1. Field of Invention
The present invention is concerned with the use of certain arylsulfonamides in the treatment of joint disease associated with chronic arthritis methods and pharmaceutical compositions therefore. In particular the invention is concerned with internal
Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic
Amido substituted naphthalenes and intermediates thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to amido substituted naphthalenes of general formula I: ##STR1## or their intermediates of general formula II: ##STR2## as described further below, and to a method for synthesizing the naphthalene derivatives. The
Treatment of dermatoses and illnesses producing inflammation
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BACKGROUND OF THE INVENTION
This invention is directed to the treatment of certain dermatoses as well as inflammation associated with various diseases. It has been known to utilize the compound 1,2,3,4-tetrahydro-1,1,4,4-tetramethyl-6-(alpha-methylstyryl)naphthalene which has the formula ##STR1##
Anti-inflammatory, disinfectant and anti-bacterial compound
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The present invention relates to a new compound with anti-inflammatory, disinfectant and anti-bacterial activity, viz. (+)-6-methoxy-.alpha.-methyl-2-naphthalene acetate of N,N"-bis (4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraaza-tetradecan-diimidoamide, possessing the formula (T) ##STR2##
The
Naphthalene-based inhibitors of anti-apoptotic proteins
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BACKGROUND
1. Field of the Invention
The present invention relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune
Naphthalene-based inhibitors of anti-apoptotic proteins
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FIELD OF THE DISCLOSURE
The disclosure relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune diseases, and/or
Naphthalene-based inhibitors of anti-apoptotic proteins
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FIELD OF THE DISCLOSURE
The disclosure relates generally to a class of compounds derived from naphthalene, such as apogossypol and derivatives thereof, for treating a variety of disorders, diseases and pathologic conditions, and more specifically, for treating cancer, autoimmune diseases, and/or
Tetrahydro-naphthalene derivatives as glucocorticoid receptor modulators
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is filed pursuant to 35 U.S.C. .sctn.371 as a United States National Phase Application of International Application No. PCT/EP2005/008763 filed 10 Aug. 2005, which claims priority from Great Britain Application No. 0418045.1 filed 12 Aug.
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