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naphthalene/stroke
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Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic
Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF THE INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR)
Tetrahydro-naphthalene derivatives
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DETAILED DESCRIPTION OF INVENTION
1. Technical Field
The present invention relates to a tetrahydro-naphthalene derivative which is useful as an active ingredient of pharmaceutical preparations. The tetrahydro-naphthalene derivative of the present invention has vanilloid receptor (VR) antagonistic
Naphthalene thromboxane synthetase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to certain naphthalenes and benzo-fused heterocycles, namely benzothiophenes, benzofurans and indoles, which are substituted by a carboxy, lower alkoxycarbonyl or carbamoyl group. Such compounds are able to selectively inhibit the action of the
Azabicyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-ht1a antagonists
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BACKGROUND OF THE INVENTION
Recent studies with the selective 5-HT.sub.1A antagonist WAY-100635 have confirmed a role for 5-HT.sub.1A receptors in learning and memory. Carli et. al. (Neuropharmacology (1999), 38(8), 1165-1173) demonstrated that WAY-100635 prevented the impairment of spatial learning
Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
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BACKGROUND OF THE INVENTION
Recent studies with the selective 5-HT.sub.1A antagonist WAY-100635 have confirmed a role for 5-HT.sub.1A receptors in learning and memory. Carli et. al. (Neuropharmacology (1999), 38(8), 1165-1173) demonstrated that WAY-100635 prevented the impairment of spatial learning
Azabicyclylmethyl derivatives of 7,8-dihydro-1,6,9,-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT.sub.1A antagonists
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Recent studies with the selective 5-HT.sub.1A antagonist WAY-100635 have confirmed a role for 5-HT.sub.1A receptors in learning and memory. Carli et. al. (Neuropharmacology (1999), 38(8), 1165-1173) demonstrated that WAY-100635 prevented the impairment of spatial learning caused by intrahippocampal
Hydroxy tetrahydro-naphthalenylurea derivatives
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TECHNICAL FIELD
The present invention relates to hydroxy-tetrahydro-naphthalenylurea derivatives which are useful as an active ingredient of pharmaceutical preparations. The hydroxy-tetrahydro-naphthalenylurea derivatives of the present invention has vanilloid receptor (VR) antagonistic activity,
Benzo-fused thromboxane synthetase inhibitors
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BACKGROUND OF THE INVENTION
This invention relates to certain naphthalenes and benzo-fused heterocycles, namely benzothiophenes, benzofurans and indoles, which are substituted by a carboxy, lower alkoxycarbonyl or carbamoyl group. Such compounds are able to selectively inhibit the action of the
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