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nasal polyps/obesitas
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Obesity-associated severe asthma represents a distinct clinical phenotype: analysis of the British Thoracic Society Difficult Asthma Registry Patient cohort according to BMI.
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BACKGROUND
Obesity has emerged as a risk factor for the development of asthma and it may also influence asthma control and airway inflammation. However, the role of obesity in severe asthma remains unclear. Thus, our objective was to explore the association between obesity (defied by BMI) and severe
The nasal airway evaluation in morbid obesity.
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The aim of the present study was to evaluate objectively the nasal patency in the obese patients. A total of 18 morbidly obese patients were recruited for the study. All of them were surgically treated because of morbid obesity using Bilo-Pancreatic Diversion (BPD) or Laparoscopic Gastric Banding
Prevalence of nasal polyps and its risk factors: Korean National Health and Nutrition Examination Survey 2009-2011.
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BACKGROUND
Although nasal polyps (NPs) are thought to be a common otorhinolaryngologic disease, there have been few population-based epidemiologic studies on the prevalence of NPs. The aim of this study is to evaluate the prevalence of NPs and the risk factors in the general Korean
Factors reducing omalizumab response in severe asthma.
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Despite adding Omalizumab to conventional therapy, several severe asthmatics still show poor disease control. We investigated the factors that may affect a reduced Omalizumab response in a large population of severe asthmatics.
340 patients were retrospectively evaluated. FEV1%, FVC%, Asthma Control
Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland.
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Background: Eosinophilic airway inflammation is common in asthma patients and appears to be associated with severe exacerbations and loss of asthma control. Objective: To describe the resource utilization and clinical characteristics of patients with eosinophilic asthma. Design: Asthma patients ≥18
Nasal nitric oxide is a marker of poor asthma control.
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Asthma control, evaluated by symptoms, exacerbations rate and lung function may be greatly influenced by comorbidities, particularly chronic rhinosinusitis (CRS). Measurement of nasal nitric oxide (nNO) is a simple way to assess the severity of CRS. We aimed to analyze the relationship between
Asthma control in severe asthmatics under treatment with omalizumab: a cross-sectional observational study in Italy.
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Few data are available on the proportion of asthmatics achieving a good asthma control (according GINA guidelines) and on the level of airway inflammation during omalizumab treatment. The aim of this cross-sectional national observational study was to assess the level of control (according to GINA
Comorbidities are associated with different features of severe asthma.
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[Relationship between comorbidity and asthma control].
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BACKGROUND
The coexistence of potentially aggravating processes is common in asthmatics, particularly in patients with difficult control. The primary aim of this study is to ascertain whether comorbidity id more common in uncontrolled patients. As a secondary aim, we propose to evaluate the
Role of omentin and chemerin in metabolic syndrome and tumor diseases.
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For the past few years adipokines have been a center of appreciation and interest. They are biologically active molecules causing pleiotropic effects. They assist in angiogenesis, adipose tissue metabolism and inflammation, and modulate tissue sensitivity for insulin. Adipokines are produced in
Patient with nasal congestion, purulent discharge, facial pain and hyposmia
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A 46-year-old female presented at the outpatient clinic with nasal congestion, purulent discharge, facial pain with pressure sensation, headache, hyposmia, and fever (38.2 Cº) that had persisted for four months. This symptomatology was worse at night or upon awakening in the morning. Three months
Prevalence and Risk Factors of Chronic Rhinosinusitus, Allergic Rhinitis, and Nasal Septal Deviation: Results of the Korean National Health and Nutrition Survey 2008-2012.
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OBJECTIVE
Chronic rhinosinusitis (CRS), allergic rhinitis (AR), and nasal septal deviation (NSD) are frequent rhinologic diseases that consume considerable health care resources.
OBJECTIVE
To determine the prevalence and risk factors of CRS, AR, and NSD in Korea.
METHODS
This study analyzed 5-year
Two novel cases expanding the phenotype of SETD2-related overgrowth syndrome.
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The SETD2-related overgrowth syndrome is also called "Luscan-Lumish syndrome" (OMIM 616831) with the clinical characteristics of intellectual disability, speech delay, macrocephaly, facial dysmorphism, and autism spectrum disorders. We report on two novel patients a 4.5-year-old boy and a
Alternative Transoral Application of Nasopharyngeal Airways.
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Transoral application of a nasopharyngeal airway (NPA) is a novel technique for difficult airway management. Clinically, it is an effective alternative for use in nonintubated dental cases under total intravenous anesthesia. This technique can help improve oxygenation and ventilation in clinical
Real-life effectiveness of mepolizumab in patients with severe refractory eosinophilic asthma and multiple comorbidities
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Background: Data on mepolizumab in patients with severe eosinophilic asthma (EA) and comorbidities are needed to assess whether randomized controlled trial results are applicable in the real world.
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