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11 hasil
Modified human tumor necrosis factor receptor-1 polypeptide or fragment thereof, and method for preparing same
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CROSS REFERENCE TO RELATED APPLICATION
This application is a National Stage of International Application No. PCT/KR2011/009914 filed Dec. 21, 2011, claiming priority based on Korean Patent Application No. 10-2010-0132955 filed Dec. 23, 2010, the contents of all of which are incorporated herein by
Modified human tumor necrosis factor receptor-1 polypeptide or fragment thereof, and method for preparing same
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/KR2010/007160 filed on Oct. 19, 2010, which claims priority from Korean Patent Application No. 10-2009-0099219, filed on Oct. 19, 2009, the contents of all of which are incorporated
24 kilodalton cytoplasmic protease activating DNA fragmentation in apoptosis
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FIELD OF THE INVENTION
The present invention relates to proteases involved in apoptosis signalling pathways, to processes for the purification of the proteases, and more particularly to methods for the use of the proteases to modulate apoptosis in target cells.
BACKGROUND OF THE INVENTION
Necrosis
Blockade of inflammatory proteases with cyclic peptides
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FIELD OF THE INVENTION
This invention relates to the use of cyclic peptides for modulating cytokine activity, including signaling and inflammatory pathways, in various diseases. More particularly, cyclic peptides possess hereto unknown biological activities, such as inhibition of sheddases and other
Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis
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BACKGROUND OF THE INVENTION
1. Technical Field of the Invention
This invention relates generally to cytoenzymology, and more particularly to methods and reagents used in cytoenzymology.
2. Discussion of the Background Art
Apoptosis, or programmed cell death, is a process that involves the activation
Composition for collecting and preserving placental stem cells and methods of using the composition
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1. INTRODUCTION
The present invention relates to improved methods and compositions for the collection of placental stem cells, e.g., by perfusion or physical and/or enzymatic disruption of a placenta or a part thereof, and methods of collecting the stem cells using the compositions. The compositions
Composition for collecting placental stem cells and methods of using the composition
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1. INTRODUCTION
The present invention relates to improved methods and compositions for the collection of placental stem cells, e.g., by perfusion or physical and/or enzymatic disruption of a placenta or a part thereof, and methods of collecting the stem cells using the compositions. The compositions
Expression system for the secretion of bioactive human granulocyte macrophage colony stimulating factor (GM-CSF) and other heterologous proteins from steptomyces
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FIELD OF THE INVENTION
This invention relates to secretion of heterologous bioactive proteins, in particular, granulocyte macrophage colony stimulating factor ("GM-CSF") by an expression system inserted into a host selected from the Streptomyces genera.
BACKGROUND OF THE INVENTION
In producing
Use of tumor factor inhibitors together with antiviral agents and therapeutic compositions thereof against HIV infection
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The present invention relates to de novo compositions of matter for the treatment of AIDS. The present invention further relates to the de novo compositions of matter containing TNF inhibitors and antiviral agents selected from the group of reverse transcriptase inhibitors, protease inhibitors, gene
Combination therapy for conditions leading to bone loss
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FIELD OF THE INVENTION
The invention relates generally to polypeptides involved in the regulation of bone metabolism. More particularly, the invention relates to a novel polypeptide, termed osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily. The polypeptide is used
TNF-.alpha. converting enzyme inhibitory agents and method of using same
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FIELD OF THE INVENTION
The invention relates to the field of metalloproteases. Specifically, the invention relates to activation or inhibition of the ADAM family of proteases. More specifically, the invention relates to activation or inhibition of the TNF-.alpha. converting enzyme (TACE).
BACKGROUND
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