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Cerebral Granuloma Mimicking Malignant Neoplasm in Patient with Seizures 21 Years After Head Trauma.
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New-onset seizure during and after brain tumor excision: a risk assessment analysis.
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OBJECTIVE Prophylactic use of antiepileptic drugs (AEDs) in seizure-naïve brain tumor patients remains a topic of debate. This study aimed to characterize a subset of patients at highest risk for new-onset perioperative seizures (i.e., intraoperative and postoperative seizures occurring within 30
Primary, Dural-Based, Ewing Sarcoma Manifesting with Seizure Activity: Presentation of a Rare Tumor Entity with Literature Review.
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[The management of patients with new epileptic seizures in the early period after resection of hemispheric tumors: two case reports and a literature review].
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Epileptic seizures developing for the first time after a neurosurgical intervention (de novo seizures) are a challenge for choosing an optimal treatment. The pathogenesis of these seizures is often associated with factors that become inactive in the early postoperative period. These seizures can not
Perioperative seizure incidence and risk factors in 223 pediatric brain tumor patients without prior seizures.
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OBJECTIVE
The incidence of, and risk factors for, perioperative seizures and the need for perioperative antiepileptic drugs (AEDs) in previously seizure-free children with brain tumors remains unclear. The authors have undertaken a review of previously seizure-free pediatric patients with brain
Seizure outcome in children with hemispheric tumors and associated intractable epilepsy: the role of tumor removal combined with seizure foci resection.
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Children harboring hemispheric tumors associated with intractable epilepsy were retrospectively reviewed to assess seizure outcome following tumor resection and electrocorticography-guided seizure foci removal. Thirteen (93%) of our patients have remained seizure-free, off anticonvulsants or on
Brain tumors presenting as a seizure disorder in infants.
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Seizures occur in 25% to 40% of children with supratentorial tumors and are the presenting complaint in 10% to 15%. However, when divided by age, only 2% of children with seizures as the presenting complaint of brain tumors were less than 1 year of age. Three children, ranging in age from 20 days to
Seizures in patients with supratentorial oligodendroglial tumours. Clinicopathological features and management considerations.
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In this study of 34 consecutive histologically confirmed oligodendroglial brain tumours (15 oligoastrocytoma, 12 oligodendroglioma, 7 anaplastic oligodendroglioma) twenty five patients (75%) presented with symptoms related to seizures. Although the seizure incidence was lowest in anaplastic
Seizure risk in brain tumor patients with conversion to generic levetiracetam.
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Breakthrough seizure activity has been reported with conversion from brand name to generic anticonvulsants. This has prompted several organizations to support physician notification of generic substitution and patient consent. Recently, a generic formulation of levetiracetam has become available.
Cancer incidence in a cohort of patients with seizure disorders.
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The incidence of cancer was evaluated in a population-based cohort of 959 patients diagnosed with seizure disorders while residents of Rochester, MN, between 1935 and 1979. For all cancer sites combined, there were 65 incidence cases for a standard morbidity ratio of 1.4. Most of the excess was
Levetiracetam for seizures in children with brain tumors and other cancers.
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Children with brain tumors and other cancers can suffer from seizures. Unfortunately, most antiepileptic therapies are metabolized by the hepatic cytochrome P450 (CYP) system. Levetiracetam, a newer anticonvulsant, does not undergo CYP metabolism and does not alter the pharmacokinetics of
Risk of seizure and its clinical implication in the patients with cerebral metastasis from lung cancer.
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BACKGROUND
The prevalence, risk factors, and clinical implication of seizure development were investigated in patients with metastatic brain tumors.
METHODS
Medical records and radiological findings were analyzed retrospectively in 258 patients with brain metastasis from lung cancer who underwent
Cortical hemosiderin is associated with seizures in patients with newly diagnosed malignant brain tumors.
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Hemorrhage is common in brain tumors. Due to characteristic magnetic field changes induced by hemosiderin it can be detected using susceptibility weighted MRI (SWI). Its relevance to clinical syndromes is unclear. Here we investigated the patterns of intra-tumoral SWI positivity (SWI(pos)) as a
Intravenous and oral levetiracetam in patients with a suspected primary brain tumor and symptomatic seizures undergoing neurosurgery: the HELLO trial.
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BACKGROUND
Levetiracetam (LEV) is a newer anticonvulsant with a favorable safety profile. There seem to be no relevant drug interactions, and an intravenous formulation is available. Therefore, LEV might be a suitable drug for the perioperative anticonvulsive therapy of patients with suspected brain
Do prophylactic anticonvulsants in patients with brain tumors decrease the incidence of seizures?
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The well-done systematic review included a moderate number of patients from randomized controlled trials with an objective diagnosis of a brain tumor. There were mild differences between the 5 studies used in the systematic review with patients in 3 of the studies undergoing surgical resection or
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